SCHEMBL10705995

SCHEMBL10705995

CCCCCc1ccc(-c2ccc(OCCO)cc2)cc1

nearest known ligand 0.75

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.75
MEN1 O00255 2/20 0.75
ALDH1A1 P00352 2/20 0.75
KMT2A Q03164 2/20 0.75
USP2 O75604 1/20 0.75
LMNA P02545 1/20 0.75
MAPK1 P28482 1/20 0.75
CASP1 P29466 1/20 0.75
SMN1; SMN2 Q16637 1/20 0.75
SLCO1B3 Q9NPD5 1/20 0.75
SLCO1B1 Q9Y6L6 1/20 0.75
CYP2D6 P10635 1/20 0.53
RARB P10826 8/20 0.53
TSHR P16473 1/20 0.53
HSD17B10 Q99714 1/20 0.53
MAPT P10636 2/20 0.52
RAB9A P51151 1/20 0.52
L3MBTL1 Q9Y468 1/20 0.52
RARA P10276 1/20 0.51
MTOR P42345 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6138541 0.97 ALDH1A1 (0.79) CYP3A4MEN1ALDH1A1KMT2AUSP2
SCHEMBL10706009 0.95 CYP3A4 (0.68) CYP3A4MEN1ALDH1A1KMT2AUSP2
SCHEMBL6138677 0.95 ALDH1A1 (0.82) CYP3A4MEN1ALDH1A1KMT2AUSP2
SCHEMBL6138468 0.95 ALDH1A1 (0.82) CYP3A4MEN1ALDH1A1KMT2AUSP2
SCHEMBL6138495 0.95 ALDH1A1 (0.82) CYP3A4MEN1ALDH1A1KMT2AUSP2
SCHEMBL6138560 0.95 ALDH1A1 (0.82) CYP3A4MEN1ALDH1A1KMT2AUSP2
SCHEMBL6138349 0.95 ALDH1A1 (0.82) CYP3A4MEN1ALDH1A1KMT2AUSP2
SCHEMBL6138455 0.95 ALDH1A1 (0.82) CYP3A4MEN1ALDH1A1KMT2AUSP2
SCHEMBL6138551 0.95 ALDH1A1 (0.82) CYP3A4MEN1ALDH1A1KMT2AUSP2
SCHEMBL6138604 0.95 ALDH1A1 (0.82) CYP3A4MEN1ALDH1A1KMT2AUSP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0171794-B1 ALCOHOL DERIVATIVES AND LIQUID CRYSTAL COMPOSITION CONTAINING THEM Chisso Corporation (JP) 1988-06-22 EP disclosed
US-4654162-A Alcohol derivatives CHISSO CORPORATION (JP) 1987-03-31 US disclosed
EP-0171794-A1 Alcohol derivatives and liquid crystal composition containing them Chisso Corporation (JP) 1986-02-19 EP disclosed