Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TET2 | Q6N021 | 4/20 | 0.39 |
| ▸ | TET3 | O43151 | 1/20 | 0.39 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.39 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.34 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.34 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10706143 | 1.00 | TET2 (0.39) | TET2TET3TET1GRIK1GRIK2 | |
| SCHEMBL364492 | 0.81 | TSHR (0.48) | TET2TET3TET1GRIK1GRIK2 | |
| SCHEMBL20335453 | 0.80 | TSHR (0.39) | TSHRHCAR2GSTP1USP2ALDH1A1 | |
| SCHEMBL3095132 | 0.77 | TET2 (0.39) | TET2TET3TET1GRIK1GRIK2 | |
| SCHEMBL9656433 | 0.76 | TSHR (0.55) | TSHRHCAR2GSTP1USP2ALDH1A1 | |
| SCHEMBL5270082 | 0.76 | TSHR (0.55) | TSHRHCAR2GSTP1USP2ALDH1A1 | |
| SCHEMBL23581952 | 0.75 | TSHR (0.35) | TSHRHCAR2GSTP1USP2ALDH1A1 | |
| SCHEMBL11811024 | 0.75 | KDM4E (0.43) | TSHRHCAR2GSTP1USP2 | |
| SCHEMBL2868662 | 0.75 | KDM4E (0.43) | TSHRHCAR2GSTP1USP2 | |
| SCHEMBL5535259 | 0.75 | TSHR (0.35) | TSHRHCAR2GSTP1USP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0069069-B1 | POLYMERISABLE COMPOSITIONS AND POLYMERISATION PRODUCTS RESULTING THEREFROM | CIBA-GEIGY AG (CH) | 1988-03-02 | — | — | EP | disclosed |
| EP-0031305-B1 | COMPOSITIONS CONTAINING ACRYLATE AND THEIR POLYMERISATION | CIBA-GEIGY AG (CH) | 1985-10-02 | — | — | EP | disclosed |
| EP-0069069-A2 | Polymerisable compositions and polymerisation products resulting therefrom | CIBA-GEIGY AG (CH) | 1983-01-05 | — | — | EP | disclosed |
| EP-0031305-A2 | Compositions containing acrylate and their polymerisation | CIBA-GEIGY AG (CH) | 1981-07-01 | — | — | EP | disclosed |