Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TET2 | Q6N021 | 4/20 | 0.39 |
| ▸ | TET3 | O43151 | 1/20 | 0.39 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.34 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.34 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5801988 | 0.86 | TSHR (0.36) | TSHRCYP2D6CYP2C19USP2ALDH1A1 | |
| SCHEMBL6036744 | 0.85 | TSHR (0.53) | TET2TET3TET1TSHRGRIK1 | |
| SCHEMBL10706149 | 0.77 | TET2 (0.39) | TET2TET3TET1TSHRGRIK1 | |
| SCHEMBL10706143 | 0.77 | TET2 (0.39) | TET2TET3TET1TSHRGRIK1 | |
| SCHEMBL14945 | 0.75 | LMNA (0.43) | TSHRUSP2ALDH1A1CYP3A4MAPT | |
| SCHEMBL364492 | 0.75 | TSHR (0.48) | TET2TET3TET1TSHRGRIK1 | |
| SCHEMBL9811825 | 0.75 | TET2 (0.47) | TET2TET3TET1GRIK1GRIK2 | |
| Acrylic Acid SCHEMBL26649873 | 0.74 | LMNA (0.37) | TSHRUSP2ALDH1A1CYP3A4MAPT | |
| SCHEMBL1437851 | 0.74 | CA1 (0.47) | TSHRUSP2ALDH1A1CYP3A4MAPT | |
| SCHEMBL27606246 | 0.74 | TSHR (0.34) | TSHRUSP2ALDH1A1CYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016093156-A1 | CLEANSING COMPOSITION CONTAINING AMORPHOUS AGGLOMERATE PARTICLE | L'OREAL (FR) | 2016-06-16 | — | — | WO | disclosed |
| US-8337822-B2 | Treatment of the hair; forms a coating resistant to external attacks such as blow drying and/or perspiration, has excellent adhesion to individual hairs, and is resistant to shampooing; polyureadimethicone for example | L'OREAL (FR) | 2012-12-25 | — | — | US | disclosed |
| US-7799093-B2 | Coloring composition of keratinous fibers comprising at least one polysiloxane/polyurea block copolymer | L'ORéAL S.A. (FR) | 2010-09-21 | — | — | US | disclosed |
| US-20080171010-A1 | Use of a polysiloxane/polyurea block copolymer for the treatment of keratinous fibers | L'OREAL S.A. (FR) | 2008-07-17 | — | — | US | disclosed |
| US-20080127429-A1 | Coloring composition of keratinous fibers comprising at least one polysiloxane/polyurea block copolymer | L'OREAL S.A. (FR) | 2008-06-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080171010-A1 | Use of a polysiloxane/polyurea block copolymer for the treatment of keratinous fibers | KRT18, POLR1C, PRKDC | TET2 2267/4885TET3 1561/4885TET1 1973/4885 |
| US-20080127429-A1 | Coloring composition of keratinous fibers comprising at least one polysiloxane/polyurea block copolymer | KRT18, PUF60, VIM | TET2 3935/4885TET3 1962/4885TET1 2121/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.