SCHEMBL10706545

SCHEMBL10706545

CCN(CC)c1ccc(C2CC(C=Cc3ccc(OC)cc3)=NN2c2ccccc2)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 6/20 0.49
▸ KMT2A Q03164 6/20 0.49
▸ USP2 O75604 2/20 0.49
▸ TDP1 Q9NUW8 1/20 0.49
▸ ALDH1A1 P00352 6/20 0.46
▸ MAPT P10636 6/20 0.46
▸ L3MBTL1 Q9Y468 6/20 0.46
▸ ATM Q13315 5/20 0.46
▸ KDM4E B2RXH2 4/20 0.46
▸ S1PR4 O95977 2/20 0.46
▸ S1PR1 P21453 2/20 0.46
▸ MAPK1 P28482 2/20 0.46
▸ GAA P10253 2/20 0.46
▸ NPSR1 Q6W5P4 2/20 0.46
▸ RXFP1 Q9HBX9 1/20 0.46
▸ LMNA P02545 3/20 0.44
▸ SMN1; SMN2 Q16637 2/20 0.44
▸ HPGD P15428 1/20 0.44
▸ RCE1 Q9Y256 1/20 0.44
▸ EGFR P00533 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12311120 0.95 MEN1 (0.47) MEN1KMT2AUSP2TDP1ALDH1A1
SCHEMBL1221038 0.93 MEN1 (0.44) MEN1KMT2AUSP2TDP1ALDH1A1
SCHEMBL132788 0.93 MEN1 (0.44) MEN1KMT2AUSP2TDP1ALDH1A1
SCHEMBL9359545 0.89 MEN1 (0.56) MEN1KMT2AUSP2TDP1ALDH1A1
SCHEMBL2024866 0.89 MEN1 (0.56) MEN1KMT2AUSP2TDP1ALDH1A1
SCHEMBL28152939 0.89 MEN1 (0.56) MEN1KMT2AUSP2TDP1ALDH1A1
SCHEMBL11264406 0.89 MEN1 (0.49) MEN1KMT2AUSP2TDP1ALDH1A1
SCHEMBL4326651 0.89 MAPT (0.42) MEN1KMT2AUSP2TDP1ALDH1A1
SCHEMBL9707149 0.89 MEN1 (0.49) MEN1KMT2AUSP2TDP1ALDH1A1
SCHEMBL13898819 0.89 MAPT (0.42) MEN1KMT2AUSP2TDP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0153145-B1 PHOTORECEPTOR KONICA CORPORATION (JP) 1988-06-08 — — EP disclosed
EP-0156481-B1 PHOTORECEPTOR KONICA CORPORATION (JP) 1988-06-08 — — EP disclosed
US-4579800-A HIGH STABILITY WITH RESPECT TO LIGHT AND HEAT KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1986-04-01 — — US disclosed
US-4576886-A ELECTROGRAPHY KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1986-03-18 — — US disclosed
EP-0156481-A2 Photoreceptor KONICA CORPORATION (JP) 1985-10-02 — — EP disclosed
EP-0153145-A2 Photoreceptor KONICA CORPORATION (JP) 1985-08-28 — — EP disclosed
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