Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 15/20 | 0.77 |
| ▸ | GABRG2 | P18507 | 15/20 | 0.77 |
| ▸ | GABRB3 | P28472 | 15/20 | 0.77 |
| ▸ | GABRA3 | P34903 | 15/20 | 0.77 |
| ▸ | GABRA2 | P47869 | 15/20 | 0.77 |
| ▸ | GABRA5 | P31644 | 14/20 | 0.77 |
| ▸ | GABRA4 | P48169 | 12/20 | 0.77 |
| ▸ | GABRA6 | Q16445 | 12/20 | 0.77 |
| ▸ | GABRP | O00591 | 5/20 | 0.65 |
| ▸ | GABRD | O14764 | 5/20 | 0.65 |
| ▸ | GABRB1 | P18505 | 5/20 | 0.65 |
| ▸ | GABRB2 | P47870 | 5/20 | 0.65 |
| ▸ | GABRE | P78334 | 5/20 | 0.65 |
| ▸ | GABRG1 | Q8N1C3 | 5/20 | 0.65 |
| ▸ | GABRG3 | Q99928 | 5/20 | 0.65 |
| ▸ | GABRQ | Q9UN88 | 5/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.65 |
| ▸ | MAPT | P10636 | 3/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10707662 | 0.90 | GABRA1 (0.76) | GABRA1GABRG2GABRB3GABRA3GABRA2 | |
| SCHEMBL10708806 | 0.89 | GABRA1 (0.74) | GABRA1GABRG2GABRB3GABRA3GABRA2 | |
| SCHEMBL10708804 | 0.89 | GABRA1 (0.73) | GABRA1GABRG2GABRB3GABRA3GABRA2 | |
| SCHEMBL10709059 | 0.88 | GABRA1 (0.71) | GABRA1GABRG2GABRB3GABRA3GABRA2 | |
| SCHEMBL9075631 | 0.87 | GABRA1 (0.77) | GABRA1GABRG2GABRB3GABRA3GABRA2 | |
| SCHEMBL11288083 | 0.87 | GABRA1 (0.77) | GABRA1GABRG2GABRB3GABRA3GABRA2 | |
| SCHEMBL7380799 | 0.85 | GABRA1 (0.74) | GABRA1GABRG2GABRB3GABRA3GABRA2 | |
| SCHEMBL10705765 | 0.82 | GABRA1 (0.53) | GABRA1GABRG2GABRB3GABRA3GABRA2 | |
| SCHEMBL10740909 | 0.81 | GABRA1 (0.77) | GABRA1GABRG2GABRB3GABRA3GABRA2 | |
| SCHEMBL7382523 | 0.80 | GABRA1 (0.76) | GABRA1GABRG2GABRB3GABRA3GABRA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0054507-B1 | 3-SUBSTITUTED BETA-CARBOLINES, PROCESS FOR THEIR PRODUCTION AND COMPOSITIONS CONTAINING THEM | SCHERING AKTIENGESELLSCHAFT (DE) | 1988-02-17 | — | — | EP | disclosed |