SCHEMBL1070769

SCHEMBL1070769

CC(C)(Cl)C=CC(C)(C)Cl

nearest known ligand 0.46

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.46
THRB P10828 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5599456 1.00 TSHR (0.46) TSHRTHRB
SCHEMBL17344228 0.88 TSHR (0.36) TSHR
SCHEMBL10794016 0.79
SCHEMBL7718037 0.79
SCHEMBL18834166 0.79
SCHEMBL2072721 0.76
SCHEMBL23504270 0.76
SCHEMBL22630670 0.76
SCHEMBL17518169 0.76
Ammonia Solution, Strong SCHEMBL2340706 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0050762-B1 PROCESS FOR THE PREPARATION OF VINYLCYCLOPROPANE DERIVATIVES NATIONAL DISTILLERS AND CHEMICAL CORPORATION (US) 1984-06-13 EP claimed
EP-3858874-B1 POLYMERISATION UNIT AND POLYMERISATION PROCESS INEOS EUROPE AG (CH) 2024-06-05 EP disclosed
WO-2023232613-A1 PROCESS FOR MANUFACTURING OF HIGHER FUNCTIONAL POLYISOBUTENES BASF SE (DE) 2023-12-07 WO disclosed
EP-3481547-B1 POLYMERISATION PROCESS INEOS EUROPE AG (CH) 2023-06-07 EP disclosed
US-11478772-B2 Polymerisation unit and polymerisation process INEOS EUROPE AG (CH) 2022-10-25 US disclosed
US-10189943-B2 Copolymers suitable for making membranes BASF SE (DE) 2019-01-29 US disclosed
EP-3114156-B1 NEW COPOLYMERS SUITABLE FOR MAKING MEMBRANES BASF SE (DE) 2017-12-20 EP disclosed
CN-104837873-B The method for preparing the polyisobutene and its derivative of functionalization 巴斯夫欧洲公司 2017-08-25 CN disclosed
EP-2928928-B1 METHOD FOR PRODUCING FUNCTIONALIZED POLYISOBUTYLENES AND DERIVATIVES THEREOF BASF SE (DE) 2017-06-21 EP disclosed
US-20170073467-A1 NEW COPOLYMERS SUITABLE FOR MAKING MEMBRANES BASF SE (DE) 2017-03-16 US disclosed
US-6852808-B2 Method for producing homopolymers and copolymers of isobutene BASF AKTIENGESELLSCHAFT (DE) 2005-02-08 US disclosed
US-20050009998-A1 Polyisobutene and polyisobutene derivatives for use in lubricant compositions BASF AKTIENGESELLSCHAFT (DE) 2005-01-13 US disclosed
US-20040171772-A1 METHOD FOR PRODUCING HOMOPOLYMERS AND COPOLYMERS OF ISOBUTENE BASF AKTIENGESELLSCHAFT (DE) 2004-09-02 US disclosed
US-20040014911-A1 Method for producing homopolymers and copolymers of isobutene BASF AKTIENGESELLSCHAFT (DE) 2004-01-22 US disclosed
US-20040015029-A1 Via cationic polymerization of isobutene in presence of initiator comprising Lewis acid, titanium chloride, borontrichloride, and 2-chloro-2-phenylpropane; for use as fuel/lubricant additives BASF AKTIENGESELLSCHAFT (DE) 2004-01-22 US disclosed
US-5332791-A Polyisobutylene hydrocarbon or polymer containing a double bond allylic to an end amino group BASF AKTIENGESELLSCHAFT (DE) 1994-07-26 US disclosed
US-5212248-A PREPARATION OF HYDROCARBONS AND POLYMERS WITH ALLYLIC CHLORIDE END GROUPS FRIEDEL-CRAFTS CATALYST BASF AKTIENGESELLSCHAFT (DE) 1993-05-18 US disclosed
EP-0435116-A2 Process for the purification of polymers of isobutylene BASF Aktiengesellschaft (DE) 1991-07-03 EP disclosed
EP-0025846-A1 Improved process for the preparation of vinylcyclopropane derivatives NATIONAL DISTILLERS AND CHEMICAL CORPORATION (US) 1981-04-01 EP disclosed
US-4252739-A ALKYLATING AGENT SUCH AS 1,4-DIHALO-2-BUTENE, AN ACTIVE METHYLENE COMPOUND, A CATALYTIC ONIUM COMPOUND, AN ALKALI METAL COMPOUND AND WATER; ONE STEP EMERY INDUSTRIES, INC. (US) 1981-02-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040015029-A1 Via cationic polymerization of isobutene in presence of initiator comprising Lewis acid, titanium chloride, borontrichloride, and 2-chloro-2-phenylpropane; for use as fuel/lubricant additives FGB, CLTB, TAF11 TSHR 1899/4885THRB 253/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.