Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | RECQL | P46063 | 2/20 | 0.49 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.49 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.49 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | CTSV | O60911 | 1/20 | 0.47 |
| ▸ | CTSL | P07711 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | GFER | P55789 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.46 |
| ▸ | ANO2 | Q9NQ90 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10706902 | 0.92 | NT5E (0.62) | NT5ETDP1MAPTRECQLDUSP3 | |
| SCHEMBL10764748 | 0.90 | TDP1 (0.58) | NT5ETDP1MAPTRECQLDUSP3 | |
| SCHEMBL11110261 | 0.86 | NT5E (0.69) | NT5ETDP1MAPTRECQLCTSV | |
| SCHEMBL10880062 | 0.85 | NT5E (0.65) | NT5ETDP1MAPTRECQLMEN1 | |
| SCHEMBL11104382 | 0.85 | NT5E (0.70) | NT5ETDP1MAPTRECQLCTSV | |
| SCHEMBL10881471 | 0.84 | NT5E (0.66) | NT5ETDP1MAPTRECQLMEN1 | |
| SCHEMBL10882284 | 0.83 | NT5E (0.65) | NT5ETDP1MAPTRECQLMEN1 | |
| SCHEMBL10708423 | 0.81 | NT5E (0.66) | NT5ETDP1MAPTRECQLMEN1 | |
| SCHEMBL10883556 | 0.81 | TDP1 (0.59) | TDP1MAPTALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL2032113 | 0.81 | NT5E (0.85) | NT5ETDP1MAPTRECQLCTSV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0126378-B1 | PREPARATION PROCESS OF ACID NITRO DYES | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-07-09 | — | — | EP | claimed |
| US-4599450-A | Process for the preparation of acid nitro dyestuffs | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-07-08 | — | — | US | claimed |
| EP-0126378-A1 | Preparation process of acid nitro dyes | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-11-28 | — | — | EP | claimed |
| EP-0165483-B1 | PROCESS FOR THE MANUFATURE OF ACID NITRO DYES | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-11-30 | — | — | EP | disclosed |
| EP-0126378-B1 | PREPARATION PROCESS OF ACID NITRO DYES | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-07-09 | — | — | EP | disclosed |
| US-4599450-A | Process for the preparation of acid nitro dyestuffs | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-07-08 | — | — | US | disclosed |
| EP-0165483-A2 | Process for the manufature of acid nitro dyes | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-12-27 | — | — | EP | disclosed |
| EP-0126378-A1 | Preparation process of acid nitro dyes | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-11-28 | — | — | EP | disclosed |