Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 2/20 | 0.65 |
| ▸ | MEN1 | O00255 | 7/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.50 |
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | GAA | P10253 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | GFER | P55789 | 2/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | BCL6 | P41182 | 1/20 | 0.45 |
| ▸ | BCOR | Q6W2J9 | 1/20 | 0.45 |
| ▸ | TBXA2R | P21731 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10708423 | 0.92 | NT5E (0.66) | NT5EMEN1KMT2AMAPTGAA | |
| SCHEMBL10762587 | 0.89 | NT5E (0.50) | NT5EMEN1KMT2AMAPTGAA | |
| SCHEMBL11110261 | 0.89 | NT5E (0.69) | NT5EMEN1KMT2AMAPTGAA | |
| SCHEMBL11104382 | 0.88 | NT5E (0.70) | NT5EMEN1KMT2AMAPTGAA | |
| SCHEMBL10702427 | 0.87 | NT5E (0.71) | NT5EMEN1KMT2AMAPTGAA | |
| SCHEMBL10880062 | 0.86 | NT5E (0.65) | NT5EMEN1KMT2AMAPTGAA | |
| SCHEMBL10881471 | 0.84 | NT5E (0.66) | NT5EMEN1KMT2AMAPTGAA | |
| SCHEMBL2032113 | 0.84 | NT5E (0.85) | NT5EMEN1KMT2AMAPTGAA | |
| SCHEMBL10707915 | 0.83 | NT5E (0.61) | NT5EMEN1KMT2AMAPTGAA | |
| SCHEMBL10706902 | 0.81 | NT5E (0.62) | NT5EMEN1KMT2AMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0126378-B1 | PREPARATION PROCESS OF ACID NITRO DYES | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-07-09 | — | — | EP | claimed |
| US-4599450-A | Process for the preparation of acid nitro dyestuffs | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-07-08 | — | — | US | claimed |
| EP-0126378-A1 | Preparation process of acid nitro dyes | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-11-28 | — | — | EP | claimed |
| US-4599450-A | Process for the preparation of acid nitro dyestuffs | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-07-08 | — | — | US | disclosed |
| US-4591359-A | Process for preparing acid nitro dyestuffs for leather | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-05-27 | — | — | US | disclosed |
| EP-0137243-A2 | Process for the manufacture of acid nitro dyes | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-04-17 | — | — | EP | disclosed |
| EP-0126378-A1 | Preparation process of acid nitro dyes | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-11-28 | — | — | EP | disclosed |