Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.62 |
| ▸ | SERPINA6 | P08185 | 5/20 | 0.62 |
| ▸ | LMNA | P02545 | 5/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.62 |
| ▸ | TSHR | P16473 | 3/20 | 0.62 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.62 |
| ▸ | SHBG | P04278 | 3/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.62 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | KCNA1 | Q09470 | 1/20 | 0.62 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.62 |
| ▸ | FNTA | P49354 | 6/20 | 0.61 |
| ▸ | FNTB | P49356 | 6/20 | 0.61 |
| ▸ | BLM | P54132 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | AR | P10275 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27915991 | 0.88 | HSD17B10 (0.67) | HSD17B10SERPINA6LMNASMN1; SMN2TSHR | |
| SCHEMBL3500094 | 0.87 | HSD17B10 (0.70) | HSD17B10SERPINA6LMNASMN1; SMN2TSHR | |
| SCHEMBL10708917 | 0.85 | HIF1A (0.63) | HSD17B10SERPINA6LMNASMN1; SMN2TSHR | |
| SCHEMBL20243021 | 0.83 | HSD17B10 (0.75) | HSD17B10SERPINA6LMNASMN1; SMN2TSHR | |
| SCHEMBL8622249 | 0.81 | HSD17B10 (0.72) | HSD17B10SERPINA6LMNASMN1; SMN2TSHR | |
| SCHEMBL1625974 | 0.80 | HSD17B10 (0.79) | HSD17B10SERPINA6LMNASMN1; SMN2TSHR | |
| SCHEMBL1625973 | 0.80 | HSD17B10 (0.79) | HSD17B10SERPINA6LMNASMN1; SMN2TSHR | |
| SCHEMBL28131473 | 0.80 | FNTA (0.65) | HSD17B10SERPINA6LMNASMN1; SMN2TSHR | |
| Cortisone SCHEMBL8584500 | 0.79 | HSD17B10 (0.74) | HSD17B10SERPINA6LMNASMN1; SMN2TSHR | |
| SCHEMBL11615772 | 0.78 | HSD17B10 (0.76) | HSD17B10SERPINA6LMNASMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0127829-B1 | IMPROVED STEROID ESTERS PREPARATION | AB LEO (SE) | 1988-02-24 | — | — | EP | disclosed |
| US-4537722-A | CARBODIIMIDES WITH ACID CATALYSTS ARE USED AS CONDENSING AGENTS | AB LEO (SE) | 1985-08-27 | — | — | US | disclosed |
| EP-0127829-A2 | Improved steroid esters preparation | AB LEO (SE) | 1984-12-12 | — | — | EP | disclosed |