Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 9/20 | 0.63 |
| ▸ | LMNA | P02545 | 2/20 | 0.63 |
| ▸ | NR3C1 | P04150 | 10/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.63 |
| ▸ | PGR | P06401 | 2/20 | 0.63 |
| ▸ | SERPINA6 | P08185 | 2/20 | 0.63 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.63 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.63 |
| ▸ | SHBG | P04278 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
| ▸ | AR | P10275 | 1/20 | 0.59 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.59 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8538851 | 0.89 | HIF1A (0.69) | HIF1ALMNANR3C1CYP2C19HSD17B10 | |
| SCHEMBL3638583 | 0.88 | HIF1A (0.68) | HIF1ALMNANR3C1CYP2C19HSD17B10 | |
| SCHEMBL10730817 | 0.88 | HIF1A (0.68) | HIF1ALMNANR3C1CYP2C19HSD17B10 | |
| SCHEMBL607956 | 0.87 | HIF1A (0.72) | HIF1ALMNANR3C1CYP2C19HSD17B10 | |
| SCHEMBL10708089 | 0.85 | HSD17B10 (0.62) | HIF1ALMNANR3C1CYP2C19HSD17B10 | |
| SCHEMBL9437393 | 0.84 | HIF1A (0.75) | HIF1ALMNANR3C1CYP2C19HSD17B10 | |
| SCHEMBL11814284 | 0.84 | HIF1A (0.81) | HIF1ALMNANR3C1CYP2C19HSD17B10 | |
| SCHEMBL16020569 | 0.82 | HIF1A (0.78) | HIF1ALMNANR3C1CYP2C19HSD17B10 | |
| SCHEMBL603002 | 0.82 | HIF1A (0.69) | HIF1ALMNANR3C1CYP2C19HSD17B10 | |
| SCHEMBL7614974 | 0.81 | HIF1A (0.77) | HIF1ALMNANR3C1CYP2C19HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0127829-B1 | IMPROVED STEROID ESTERS PREPARATION | AB LEO (SE) | 1988-02-24 | — | — | EP | disclosed |
| US-4537722-A | CARBODIIMIDES WITH ACID CATALYSTS ARE USED AS CONDENSING AGENTS | AB LEO (SE) | 1985-08-27 | — | — | US | disclosed |
| EP-0127829-A2 | Improved steroid esters preparation | AB LEO (SE) | 1984-12-12 | — | — | EP | disclosed |