Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 3/20 | 0.55 |
| ▸ | FAAH | O00519 | 3/20 | 0.55 |
| ▸ | THRA | P10827 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.48 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | RARB | P10826 | 1/20 | 0.45 |
| ▸ | PLK1 | P53350 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10707070 | 0.95 | THRB (0.61) | THRBFAAHTHRAALDH1A1HSD17B10 | |
| SCHEMBL10709883 | 0.94 | THRB (0.61) | THRBFAAHTHRAALDH1A1HSD17B10 | |
| SCHEMBL233924 | 0.92 | THRB (0.63) | THRBFAAHTHRAHPGDALDH1A1 | |
| SCHEMBL10708974 | 0.88 | THRB (0.60) | THRBTHRAHPGDALDH1A1HSD17B10 | |
| SCHEMBL10706439 | 0.88 | THRB (0.69) | THRBFAAHTHRAHPGDALDH1A1 | |
| SCHEMBL10707778 | 0.88 | THRB (0.52) | THRBFAAHTHRAHPGDALDH1A1 | |
| SCHEMBL17472998 | 0.87 | THRB (0.68) | THRBFAAHTHRAHPGDALDH1A1 | |
| SCHEMBL10707176 | 0.87 | THRB (0.68) | THRBFAAHTHRAHPGDALDH1A1 | |
| SCHEMBL237889 | 0.87 | RARB (0.60) | THRBTHRAHPGDALDH1A1HSD17B10 | |
| SCHEMBL17473161 | 0.87 | THRB (0.68) | THRBFAAHTHRAHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0184012-B1 | LIQUID CRYSTAL COMPOSITIONS | BAYER AG (DE) | 1988-01-07 | — | — | EP | disclosed |
| EP-0184012-A1 | Liquid crystal compositions | BAYER AG (DE) | 1986-06-11 | — | — | EP | disclosed |