Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.41 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGDS | O60760 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9328736 | 0.88 | KDM4E (0.48) | HIF1AKMT2AHDAC3HDAC1HDAC6 | |
| SCHEMBL3505795 | 0.84 | MAOB (0.53) | HIF1AKMT2AHDAC3HDAC1HDAC6 | |
| Hydrochloric Acid SCHEMBL5618243 | 0.83 | KMT2A (0.51) | HIF1AKMT2AHDAC3HDAC1HDAC6 | |
| SCHEMBL7218537 | 0.80 | TLR7 (0.43) | HIF1AHDAC3HDAC1HDAC6HDAC2 | |
| SCHEMBL11500010 | 0.78 | NPSR1 (0.49) | KMT2AKDM4EALDH1A1TLR7MAPT | |
| SCHEMBL9331727 | 0.76 | MEN1 (0.50) | HIF1AKMT2AHDAC3HDAC1HDAC6 | |
| SCHEMBL299830 | 0.74 | RAB9A (0.59) | KMT2AKDM4EALDH1A1TLR7MAPT | |
| SCHEMBL9329351 | 0.73 | HIF1A (0.67) | HIF1AHDAC3HDAC1HDAC6HDAC2 | |
| SCHEMBL27709048 | 0.73 | RAB9A (0.37) | HIF1AKMT2AKDM4EALDH1A1PANK3 | |
| SCHEMBL292888 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4764522-A | ANTIDEPRESSANT, ANTIPARKINSON DISEASE | HOFFMANN-LA ROCHE INC. (US) | 1988-08-16 | — | — | US | disclosed |