Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 3/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.44 |
| ▸ | FABP3 | P05413 | 2/20 | 0.42 |
| ▸ | FABP4 | P15090 | 2/20 | 0.42 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.39 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9193846 | 0.84 | ALDH1A1 (0.40) | GABRA1GABRB2FABP3FABP4FABP5 | |
| SCHEMBL12500701 | 0.83 | HIF1A (0.42) | GABRA1GABRB2FABP3FABP4HIF1A | |
| SCHEMBL12695054 | 0.80 | PTGS1 (0.48) | HIF1AALDH1A1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL12500702 | 0.80 | ALDH1A1 (0.40) | GABRA1GABRB2HIF1AALDH1A1CYP3A4 | |
| SCHEMBL11951677 | 0.78 | HIF1A (0.39) | GABRA1GABRB2HIF1AALDH1A1CYP3A4 | |
| SCHEMBL18068085 | 0.78 | PDK2 (0.40) | GABRA1GABRB2FABP3FABP4FABP5 | |
| SCHEMBL31283556 | 0.77 | FABP3 (0.37) | GABRA1GABRB2FABP3FABP4FABP5 | |
| SCHEMBL26300933 | 0.76 | PTGS1 (0.53) | HIF1AALDH1A1CYP2D6CYP2C9TRPA1 | |
| SCHEMBL12695019 | 0.76 | HDAC4 (0.42) | HIF1AALDH1A1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL15801267 | 0.76 | ACE2 (0.41) | HIF1AALDH1A1CYP2D6CYP2C9TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0188204-B1 | PROCESS FOR THE FABRICATION OF THERMOSETTING ALIPHATIC POLYCARBONATES | BAYER AG (DE) | 1988-06-15 | — | — | EP | disclosed |
| US-4694065-A | Process for the production of duromeric aliphatic polycarbonates | BAYER AKTIENGESELLSCHAFT (DE) | 1987-09-15 | — | — | US | disclosed |