SCHEMBL10708477

SCHEMBL10708477

O=C(OCc1ccccc1)c1ccc(OC(=O)c2ccc(O)cc2)cc1

nearest known ligand 0.81

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.81
KMT2A Q03164 6/20 0.67
TDP1 Q9NUW8 3/20 0.67
SLC6A2 P23975 2/20 0.67
SLC6A3 Q01959 2/20 0.67
MEN1 O00255 2/20 0.67
ESR1 P03372 1/20 0.60
ESR2 Q92731 1/20 0.60
MAPT P10636 6/20 0.57
ALDH1A1 P00352 4/20 0.57
HPGD P15428 1/20 0.57
TSHR P16473 1/20 0.55
PARP10 Q53GL7 1/20 0.53
GAA P10253 3/20 0.52
RAB9A P51151 3/20 0.52
HSP90AA1 P07900 1/20 0.52
CYP2C19 P33261 2/20 0.50
NPC1 O15118 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
KDM4E B2RXH2 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10344103 0.95 KMT2A (0.73) LMNAKMT2ATDP1SLC6A2SLC6A3
SCHEMBL9696121 0.95 KMT2A (0.73) LMNAKMT2ATDP1SLC6A2SLC6A3
SCHEMBL8198304 0.94 KMT2A (0.77) LMNAKMT2ATDP1SLC6A2SLC6A3
SCHEMBL27578 0.90 LMNA (1.00) LMNAKMT2ATDP1SLC6A2SLC6A3
SCHEMBL17212781 0.89 KMT2A (0.65) LMNAKMT2ATDP1SLC6A2SLC6A3
Benzyl Benzoate SCHEMBL28087287 0.89 TDP1 (0.79) LMNAKMT2ATDP1SLC6A2SLC6A3
SCHEMBL2519911 0.89 LMNA (0.96) LMNAKMT2ATDP1SLC6A2SLC6A3
Hydrochloric Acid SCHEMBL28511050 0.89 LMNA (0.96) LMNAKMT2ATDP1SLC6A2SLC6A3
SCHEMBL10344295 0.88 KMT2A (0.68) LMNAKMT2ATDP1SLC6A2SLC6A3
SCHEMBL17212838 0.88 KMT2A (0.63) LMNAKMT2ATDP1SLC6A2SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0169246-A1 PARAHYDROXYBENZOATE COMPOUND Yoshitomi Pharmaceutical Industries, Ltd. (JP) 1986-01-29 EP claimed
JP-60199859-A None JP disclosed
US-7348044-B2 Liquid crystal composition and liquid crystal element FUJIFILM CORPORATION (JP) 2008-03-25 US disclosed
EP-0154336-B1 THERMOSENSITIVE RECORDING SHEET JUJO PAPER CO., LTD. (JP) 1988-10-26 EP disclosed
US-4573062-A HYDROXYBENZ/YLOXYBENZOIC ACID COLOR DEVELOPER AND LEUCO DYE JUJO PAPER CO., LTD. (JP) 1986-02-25 US disclosed
EP-0169246-A1 PARAHYDROXYBENZOATE COMPOUND Yoshitomi Pharmaceutical Industries, Ltd. (JP) 1986-01-29 EP disclosed
EP-0169246-A1 PARAHYDROXYBENZOATE COMPOUND Yoshitomi Pharmaceutical Industries, Ltd. (JP) 1986-01-29 EP disclosed
JP-S60199859-A P-HYDROXYBENZOIC ACID DERIVATIVE YOSHITOMI PHARMACEUT IND LTD 1985-10-09 JP disclosed
EP-0154336-A2 Thermosensitive recording sheet JUJO PAPER CO., LTD. (JP) 1985-09-11 EP disclosed
WO-1985003289-A1 PARAHYDROXYBENZOATE COMPOUND YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) 1985-08-01 WO disclosed