Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10709432 | 1.00 | TDP1 (0.59) | TDP1ALDH1A1LMNAADRA2ACNR1 | |
| SCHEMBL10706160 | 1.00 | TDP1 (0.59) | TDP1ALDH1A1LMNAADRA2ACNR1 | |
| SCHEMBL10710325 | 1.00 | TDP1 (0.59) | TDP1ALDH1A1LMNAADRA2ACNR1 | |
| SCHEMBL10706162 | 1.00 | TDP1 (0.59) | TDP1ALDH1A1LMNAADRA2ACNR1 | |
| SCHEMBL10709435 | 1.00 | TDP1 (0.59) | TDP1ALDH1A1LMNAADRA2ACNR1 | |
| SCHEMBL13824818 | 0.94 | TDP1 (0.52) | TDP1ALDH1A1LMNAADRA2ACNR1 | |
| SCHEMBL29391915 | 0.92 | TDP1 (0.69) | TDP1ALDH1A1LMNAADRA2ACNR1 | |
| SCHEMBL11270951 | 0.92 | TDP1 (0.69) | TDP1ALDH1A1LMNAADRA2ACNR1 | |
| SCHEMBL11268455 | 0.92 | TDP1 (0.69) | TDP1ALDH1A1LMNAADRA2ACNR1 | |
| SCHEMBL118147 | 0.92 | TDP1 (0.69) | TDP1ALDH1A1LMNAADRA2ACNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0145179-B1 | HALO((PHENOXYPYRIDYL)METHYL)ESTERS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS INSECTICIDES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-11-23 | — | — | EP | disclosed |