Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.69 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | ATM | Q13315 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29391915 | 1.00 | TDP1 (0.69) | TDP1ALDH1A1LMNAATML3MBTL1 | |
| SCHEMBL118147 | 1.00 | TDP1 (0.69) | TDP1ALDH1A1LMNAATML3MBTL1 | |
| SCHEMBL11270951 | 1.00 | TDP1 (0.69) | TDP1ALDH1A1LMNAATML3MBTL1 | |
| SCHEMBL11505494 | 0.93 | TDP1 (0.59) | TDP1ALDH1A1LMNAATML3MBTL1 | |
| SCHEMBL11505296 | 0.93 | TDP1 (0.59) | TDP1ALDH1A1LMNAATML3MBTL1 | |
| SCHEMBL10706162 | 0.92 | TDP1 (0.59) | TDP1ALDH1A1LMNAATML3MBTL1 | |
| SCHEMBL10710325 | 0.92 | TDP1 (0.59) | TDP1ALDH1A1LMNAATML3MBTL1 | |
| SCHEMBL10709432 | 0.92 | TDP1 (0.59) | TDP1ALDH1A1LMNAATML3MBTL1 | |
| SCHEMBL10706160 | 0.92 | TDP1 (0.59) | TDP1ALDH1A1LMNAATML3MBTL1 | |
| SCHEMBL10710331 | 0.92 | TDP1 (0.59) | TDP1ALDH1A1LMNAATML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4342770-A | 3-(2,2-DICHLOROETHENYL)2,2-DIMETHYL-CYCLOPROPANE CARBOXYLIC ACID: CYANO (6-PHENOXY-2-PYRIDINYL) METHYL ESTER | DOW CHEMICAL COMPANY LIMITED (GB) | 1982-08-03 | — | — | US | claimed |
| US-4163787-A | Substituted pyridine methyl esters of cyclopropane carboxylic acids and their use as insecticides | THE DOW CHEMICAL COMPANY (US) | 1979-08-07 | — | — | US | claimed |
| US-4281133-A | INSECTICIDES | THE DOW CHEMICAL COMPANY (US) | 1981-07-28 | — | — | US | disclosed |
| US-4256893-A | INSECTICIDES | THE DOW CHEMICAL COMPANY (US) | 1981-03-17 | — | — | US | disclosed |
| US-4163787-A | Substituted pyridine methyl esters of cyclopropane carboxylic acids and their use as insecticides | THE DOW CHEMICAL COMPANY (US) | 1979-08-07 | — | — | US | disclosed |