Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | HTT | P42858 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | RECQL | P46063 | 1/20 | 0.59 |
| ▸ | BLM | P54132 | 1/20 | 0.59 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.59 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.59 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | TYR | P14679 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.50 |
| ▸ | P4HB | P07237 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL869219 | 1.00 | MAPT (0.59) | MAPTMEN1HTTKMT2AFTO | |
| SCHEMBL1029869 | 1.00 | MAPT (0.59) | MAPTMEN1HTTKMT2AFTO | |
| SCHEMBL20777527 | 1.00 | MAPT (0.59) | MAPTMEN1HTTKMT2AFTO | |
| SCHEMBL3695146 | 1.00 | MAPT (0.59) | MAPTMEN1HTTKMT2AFTO | |
| SCHEMBL29661300 | 1.00 | MAPT (0.59) | MAPTMEN1HTTKMT2AFTO | |
| SCHEMBL597089 | 1.00 | MAPT (0.59) | MAPTMEN1HTTKMT2AFTO | |
| SCHEMBL20777529 | 0.95 | CYP3A4 (0.55) | MAPTMEN1HTTKMT2AFTO | |
| SCHEMBL402758 | 0.95 | CYP3A4 (0.55) | MAPTMEN1HTTKMT2AFTO | |
| SCHEMBL1032639 | 0.95 | CYP3A4 (0.55) | MAPTMEN1HTTKMT2AFTO | |
| SCHEMBL10606489 | 0.95 | CYP3A4 (0.55) | MAPTMEN1HTTKMT2AFTO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0174477-B1 | MEANS AND METHOD FOR DETERMINING ANTIMICROBIAL-ACTIVEN SUBSTANCES | MERCK PATENT GmbH (DE) | 1988-03-30 | — | — | EP | disclosed |
| EP-0174477-A1 | Means and method for determining antimicrobial-activen substances | MERCK PATENT GmbH (DE) | 1986-03-19 | — | — | EP | disclosed |