SCHEMBL869219

SCHEMBL869219

O=C1OC2(c3ccc(O)cc3Oc3cc(O[C@@H]4O[C@H](CO)[C@H](O)[C@H](O)[C@H]4O)ccc32)c2ccccc21

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.59
MEN1 O00255 2/20 0.59
HTT P42858 2/20 0.59
KMT2A Q03164 2/20 0.59
FTO Q9C0B1 2/20 0.59
HPGD P15428 1/20 0.59
CYP2C19 P33261 1/20 0.59
RECQL P46063 1/20 0.59
BLM P54132 1/20 0.59
SMAD3 P84022 1/20 0.59
PRMT1 Q99873 1/20 0.59
ACE2 Q9BYF1 1/20 0.59
TDP1 Q9NUW8 1/20 0.59
CYP3A4 P08684 1/20 0.51
TYR P14679 4/20 0.50
LMNA P02545 2/20 0.50
USP2 O75604 1/20 0.50
ALDH1A1 P00352 1/20 0.50
TRPA1 O75762 1/20 0.50
P4HB P07237 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10710403 1.00 MAPT (0.59) MAPTMEN1HTTKMT2AFTO
SCHEMBL1029869 1.00 MAPT (0.59) MAPTMEN1HTTKMT2AFTO
SCHEMBL20777527 1.00 MAPT (0.59) MAPTMEN1HTTKMT2AFTO
SCHEMBL3695146 1.00 MAPT (0.59) MAPTMEN1HTTKMT2AFTO
SCHEMBL29661300 1.00 MAPT (0.59) MAPTMEN1HTTKMT2AFTO
SCHEMBL597089 1.00 MAPT (0.59) MAPTMEN1HTTKMT2AFTO
SCHEMBL20777529 0.95 CYP3A4 (0.55) MAPTMEN1HTTKMT2AFTO
SCHEMBL402758 0.95 CYP3A4 (0.55) MAPTMEN1HTTKMT2AFTO
SCHEMBL1032639 0.95 CYP3A4 (0.55) MAPTMEN1HTTKMT2AFTO
SCHEMBL10606489 0.95 CYP3A4 (0.55) MAPTMEN1HTTKMT2AFTO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 401 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117165655-A Rapid pathogen-specific enzymatic drug sensitivity analysis method 浙江大学 2023-12-05 CN claimed
US-9701968-B2 Biological indicator AMERICAN STERILIZER COMPANY (US) 2017-07-11 US claimed
US-20160312263-A1 BIOLOGICAL INDICATOR AMERICAN STERILIZER CO (US) 2016-10-27 US claimed
US-20160102335-A1 BIOLOGICAL INDICATOR AMERICAN STERILIZER COMPANY 2016-04-14 US claimed
US-8895239-B2 Genetically engineered biological indicator AMERICAN STERILIZER COMPANY (US) 2014-11-25 US claimed
EP-2084293-B1 GENETICALLY ENGINEERED BIOLOGICAL INDICATOR AMERICAN STERILIZER CO (US) 2014-08-13 EP claimed
US-8507248-B2 Genetically engineered biological indicator AMERICAN STERILIZER COMPANY (US) 2013-08-13 US claimed
US-20130130292-A1 Method for detecting replication or colonization of a biological therapeutic GENELUX CORPORATION 2013-05-23 US claimed
US-20100267044-A1 GENETICALLY ENGINEERED BIOLOGICAL INDICATOR FRANCISKOVICH PHILLIP P 2010-10-21 US claimed
EP-2084293-A2 GENETICALLY ENGINEERED BIOLOGICAL INDICATOR American Sterilizer Company (US) 2009-08-05 EP claimed
WO-2008079469-A2 GENETICALLY ENGINEERED BIOLOGICAL INDICATOR AMERICAN STERILIZER COMPANY (US) 2008-07-03 WO claimed
US-20080070231-A1 Reporter genes taken up by microorganism, and repressor gene inhibits expression AMERICAN STERILIZER COMPANY 2008-03-20 US claimed
US-5604091-A ENZYME DONOR POLYPEPTIDE HAVING SPECIFIED AMINO ACID SEQUENCE; QUALITATIVE AND QUANTITATIVE ANALYSIS MICROGENICS CORPORATION (US) 1997-02-18 US claimed
EP-0199801-A4 METHODS FOR PROTEIN BINDING ENZYME COMPLEMENTATION ASSAYS. MICROGENICS CORP (US) 1988-12-15 EP claimed
EP-0199801-A1 METHODS FOR PROTEIN BINDING ENZYME COMPLEMENTATION ASSAYS. MICROGENICS CORP (US) 1986-11-05 EP claimed
WO-1986002666-A1 METHODS FOR PROTEIN BINDING ENZYME COMPLEMENTATION ASSAYS MICROGENICS CORPORATION (US) 1986-05-09 WO claimed
US-12043653-B2 Efficient delivery of therapeutic molecules to cells of the inner ear MASSACHUSETTS EYE AND EAR INFIRMARY (US) 2024-07-23 US disclosed
CN-118348260-A Parkinson disease diagnosis marker combination and application thereof 香港中文大学(深圳) 2024-07-16 CN disclosed
EP-0199801-A1 METHODS FOR PROTEIN BINDING ENZYME COMPLEMENTATION ASSAYS. MICROGENICS CORP (US) 1986-11-05 EP disclosed
WO-1986002666-A1 METHODS FOR PROTEIN BINDING ENZYME COMPLEMENTATION ASSAYS MICROGENICS CORPORATION (US) 1986-05-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12043653-B2 Efficient delivery of therapeutic molecules to cells of the inner ear HES1, NOTCH1, NOTCH2 MAPT 3320/4885MEN1 254/4885HTT 2538/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.