Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 6/20 | 0.51 |
| ▸ | TDP2 | O95551 | 3/20 | 0.47 |
| ▸ | LAP3 | P28838 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | PTPRC | P08575 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10711747 | 0.81 | CREBBP (0.43) | MAPTKMT2AKDM4EALDH1A1LMNA | |
| SCHEMBL10712231 | 0.81 | PGR (0.62) | PGRTDP2MAPTGSK3BKMT2A | |
| SCHEMBL10711960 | 0.80 | PGR (0.47) | PGRTDP2MAPTGSK3BKMT2A | |
| SCHEMBL10715133 | 0.80 | PGR (0.72) | PGRTDP2MAPTGSK3B | |
| SCHEMBL10712211 | 0.79 | KMT2A (0.45) | TDP2MAPTGSK3BPTPRCKMT2A | |
| SCHEMBL11427524 | 0.77 | KMT2A (0.47) | PGRTDP2MAPTKMT2AKDM4E | |
| SCHEMBL10712932 | 0.76 | CREBBP (0.34) | TDP2MAPTKMT2A | |
| SCHEMBL10712773 | 0.73 | TDP1 (0.42) | PGRTDP2MAPTKMT2AKDM4E | |
| SCHEMBL11427311 | 0.71 | PGR (0.50) | PGRKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL10921424 | 0.71 | CCNB2 (0.39) | MAPTGSK3BKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670566-A | ANTIIFLAMMATORY AGENTS, ANTICOAGULANTS | A. H. ROBINS COMPANY, INCORPORATED (US) | 1987-06-02 | — | — | US | disclosed |
| EP-0089426-B1 | 2-AMINO-6-BIPHENYLACETIC ACIDS | A.H. ROBINS COMPANY, INCORPORATED (US) | 1986-06-11 | — | — | EP | disclosed |
| US-4440785-A | Methods of using 2-aminobiphenylacetic acids, esters, and metal salts thereof to treat inflammation | A. H. ROBINS COMPANY, INC. (US) | 1984-04-03 | — | — | US | disclosed |
| EP-0089426-A1 | 2-Amino-6-biphenylacetic acids | A.H. ROBINS COMPANY, INCORPORATED (US) | 1983-09-28 | — | — | EP | disclosed |
| US-4333951-A | MUSCLE RELAXANTS, ANTIINFLAMMATORY AGENTS | A. H. ROBINS COMPANY, INC. (US) | 1982-06-08 | — | — | US | disclosed |