Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 9/20 | 0.64 |
| ▸ | AGTR1 | P30556 | 9/20 | 0.64 |
| ▸ | AGTR2 | P50052 | 6/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.64 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.64 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.64 |
| ▸ | USP2 | O75604 | 1/20 | 0.64 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.64 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.64 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.64 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.64 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.64 |
| ▸ | ACE | P12821 | 1/20 | 0.64 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.64 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.64 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.64 |
| ▸ | PDE4A | P27815 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7302973 | 0.93 | AGTR1 (0.74) | PPARGAGTR1AGTR2KDM4EABCC3 | |
| SCHEMBL8788047 | 0.88 | PPARG (0.72) | PPARG | |
| SCHEMBL7305786 | 0.85 | PPARG (0.86) | PPARGAGTR1AGTR2KDM4EABCC3 | |
| SCHEMBL8789679 | 0.83 | AGTR1 (0.70) | PPARGAGTR1AGTR2 | |
| SCHEMBL7302980 | 0.81 | AGTR1 (0.58) | PPARGAGTR1AGTR2KDM4EABCC3 | |
| SCHEMBL7311394 | 0.80 | AGTR1 (0.72) | PPARGAGTR1AGTR2KDM4EABCC3 | |
| SCHEMBL9044757 | 0.79 | AGTR1 (0.73) | PPARGAGTR1AGTR2KDM4EABCC3 | |
| SCHEMBL8847502 | 0.79 | AGTR1 (0.81) | PPARGAGTR1AGTR2KDM4EABCC3 | |
| SCHEMBL813386 | 0.79 | AGTR1 (0.73) | PPARGAGTR1AGTR2KDM4EABCC3 | |
| SCHEMBL8266757 | 0.79 | AGTR1 (0.82) | PPARGAGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2445888-B1 | Process for preparing telmisartan | INKE SA (ES) | 2013-08-07 | — | — | EP | disclosed |
| EP-2445888-A1 | PROCESS FOR PREPARING TELMISARTAN | INKE, S.A. (ES) | 2012-05-02 | — | — | EP | disclosed |
| EP-2277866-A1 | Process for preparing telmisartan | INKE, S.A. (ES) | 2011-01-26 | — | — | EP | disclosed |
| WO-2010149565-A1 | PROCESS FOR PREPARING TELMISARTAN | INKE, S.A. (ES) | 2010-12-29 | — | — | WO | disclosed |