Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 20/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL388655 | 0.90 | GPR119 (0.54) | GPR119CYP2C9KCNH2 | |
| SCHEMBL391274 | 0.89 | GPR119 (0.59) | GPR119CYP2C9KCNH2 | |
| SCHEMBL389832 | 0.87 | GPR119 (0.68) | GPR119CYP2C9KCNH2 | |
| SCHEMBL3164031 | 0.81 | GPR119 (0.43) | GPR119CYP2C9KCNH2 | |
| SCHEMBL3164062 | 0.80 | GPR119 (0.47) | GPR119CYP2C9KCNH2 | |
| SCHEMBL389047 | 0.79 | GPR119 (0.60) | GPR119CYP2C9 | |
| SCHEMBL390920 | 0.78 | GPR119 (0.65) | GPR119CYP2C9 | |
| SCHEMBL3171681 | 0.78 | GPR119 (0.54) | GPR119CYP2C9KCNH2 | |
| SCHEMBL13451418 | 0.77 | GPR119 (0.64) | GPR119CYP2C9KCNH2 | |
| SCHEMBL390583 | 0.77 | GPR119 (0.69) | GPR119CYP2C9KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2004157-B1 | USE OF GPR119 RECEPTOR AGONISTS FOR INCREASING BONE MASS AND FOR TREATING OSTEOPOROSIS, AS WELL AS COMBINATION THERAPY RELATING THERETO | ARENA PHARM INC (US) | 2011-01-12 | — | — | EP | disclosed |