Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.74 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.74 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | CASP1 | P29466 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.41 |
| ▸ | MAOA | P21397 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3843446 | 0.91 | TSHR (0.68) | TSHRMAPK1CYP3A4CASP1RECQL | |
| SCHEMBL29402206 | 0.91 | TSHR (0.68) | TSHRMAPK1CYP3A4CASP1RECQL | |
| SCHEMBL3867382 | 0.91 | TSHR (0.68) | TSHRMAPK1CYP3A4CASP1RECQL | |
| SCHEMBL29405287 | 0.89 | TSHR (0.65) | TSHRMAPK1CYP3A4CASP1RECQL | |
| SCHEMBL8974219 | 0.89 | TSHR (0.65) | TSHRMAPK1CYP3A4CASP1RECQL | |
| SCHEMBL8167656 | 0.87 | TSHR (0.63) | TSHRMAPK1CYP3A4CASP1RECQL | |
| SCHEMBL7586287 | 0.87 | TSHR (0.63) | TSHRMAPK1CYP3A4CASP1RECQL | |
| SCHEMBL125470 | 0.85 | TSHR (0.74) | TSHRMAPK1CYP3A4CASP1RECQL | |
| SCHEMBL29410732 | 0.85 | TSHR (1.00) | TSHRMAPK1CYP3A4CASP1RECQL | |
| SCHEMBL39591 | 0.85 | TSHR (1.00) | TSHRMAPK1CYP3A4CASP1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0201778-B1 | (METH)-ACRYLIC-ACID ESTERS AND THEIR USE | BAYER AG (DE) | 1988-12-28 | — | — | EP | disclosed |
| EP-0201778-A1 | (Meth)-acrylic-acid esters and their use | BAYER AG (DE) | 1986-11-20 | — | — | EP | disclosed |