Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24710719 | 0.94 | TSHR (0.61) | TSHRMAPK1CYP3A4CASP1RECQL | |
| SCHEMBL9651762 | 0.92 | TSHR (0.59) | TSHRMAPK1CYP3A4CASP1RECQL | |
| SCHEMBL2263254 | 0.92 | TSHR (0.59) | TSHRMAPK1CYP3A4CASP1RECQL | |
| SCHEMBL15319724 | 0.92 | TSHR (0.59) | TSHRMAPK1CYP3A4CASP1RECQL | |
| SCHEMBL29402206 | 0.91 | TSHR (0.68) | TSHRMAPK1CYP3A4CASP1RECQL | |
| SCHEMBL3843446 | 0.91 | TSHR (0.68) | TSHRMAPK1CYP3A4CASP1RECQL | |
| SCHEMBL29405287 | 0.89 | TSHR (0.65) | TSHRMAPK1CYP3A4CASP1RECQL | |
| SCHEMBL8974219 | 0.89 | TSHR (0.65) | TSHRMAPK1CYP3A4CASP1RECQL | |
| SCHEMBL3867382 | 0.87 | TSHR (0.68) | TSHRMAPK1CYP3A4CASP1RECQL | |
| SCHEMBL10714404 | 0.87 | TSHR (0.74) | TSHRMAPK1CYP3A4CASP1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110961151-B | Ruthenium-copper bimetallic catalyst, preparation method and application thereof | 扬州大学 | 2022-08-12 | — | — | CN | claimed |
| CN-110961151-A | Ruthenium-copper bimetallic catalyst, preparation method and application thereof | 扬州大学 | 2020-04-07 | — | — | CN | claimed |
| WO-2023044685-A1 | HIGH-THROUGHPUT OIL-WATER SEPARATION COMPOSITE METAL MESH, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 苏州大学 | 2023-03-30 | — | — | WO | disclosed |
| WO-2022261352-A1 | PERFLUOROALKANE SUBSTITUTED PYRAZOLO[3,4-D]PYRIMIDIN AND PYRROLO[2,3-D]PYRIMIDIN COMPOUNDS AND USES THEREOF | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) | 2022-12-15 | — | — | WO | disclosed |
| CN-110961151-B | Ruthenium-copper bimetallic catalyst, preparation method and application thereof | 扬州大学 | 2022-08-12 | — | — | CN | disclosed |
| CN-113713431-A | High-flux oil-water separation composite metal net and preparation method and application thereof | 苏州大学 | 2021-11-30 | — | — | CN | disclosed |
| CN-110961151-A | Ruthenium-copper bimetallic catalyst, preparation method and application thereof | 扬州大学 | 2020-04-07 | — | — | CN | disclosed |
| US-6048869-A | REDUCTASE INHIBITORS | MERCK & CO., INC. (US) | 2000-04-11 | — | — | US | disclosed |
| US-4001406-A | BENZENEDISULFONAMIDES AS ANTHELMINTIC AGENTS | MERCK & CO., INC. (US) | 1977-01-04 | — | — | US | disclosed |