SCHEMBL10714830

SCHEMBL10714830

[S].c1ccc2sc(SNC3CCCCC3)nc2c1

nearest known ligand 0.97

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.97
HPGD P15428 5/20 0.97
TDP1 Q9NUW8 2/20 0.97
TXN P10599 1/20 0.58
NPC1 O15118 4/20 0.56
RAB9A P51151 4/20 0.56
TSHR P16473 3/20 0.56
MAOB P27338 1/20 0.54
CYP1A2 P05177 4/20 0.53
CYP2D6 P10635 4/20 0.53
KMT2A Q03164 4/20 0.52
MEN1 O00255 3/20 0.52
NFKB1 P19838 1/20 0.52
NFKB2 Q00653 1/20 0.52
RELA Q04206 1/20 0.52
HSD17B10 Q99714 2/20 0.50
FBP1 P09467 2/20 0.50
ADRA2A P08913 1/20 0.50
ADORA3 P0DMS8 1/20 0.50
DRD2 P14416 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL80270 0.99 ALDH1A1 (1.00) ALDH1A1HPGDTDP1TXNNPC1
SCHEMBL29658287 0.99 ALDH1A1 (1.00) ALDH1A1HPGDTDP1TXNNPC1
SCHEMBL11445594 0.97 ALDH1A1 (0.97) ALDH1A1HPGDTDP1TXNNPC1
SCHEMBL22607683 0.92 ALDH1A1 (0.87) ALDH1A1HPGDTDP1TXNNPC1
SCHEMBL29003989 0.91 ALDH1A1 (0.86) ALDH1A1HPGDTDP1TXNNPC1
Guanidine SCHEMBL10893242 0.91 ALDH1A1 (0.85) ALDH1A1HPGDTDP1TXNNPC1
SCHEMBL6290782 0.89 ALDH1A1 (0.81) ALDH1A1HPGDTDP1TXNNPC1
SCHEMBL18398036 0.84 ALDH1A1 (0.75) ALDH1A1HPGDTDP1TXNNPC1
SCHEMBL18407699 0.84 ALDH1A1 (0.75) ALDH1A1HPGDTDP1TXNNPC1
SCHEMBL30350291 0.84 ALDH1A1 (0.75) ALDH1A1HPGDTDP1TXNNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0253365-A2 Rubber composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1988-01-20 EP disclosed
EP-0004711-A2 Process for the cross-linking of polymers Vulnax International Limited (GB) 1979-10-17 EP disclosed