Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | MAPK8 | P45983 | 5/20 | 0.39 |
| ▸ | MAPK9 | P45984 | 5/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 5/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9398168 | 0.87 | ADRA2A (0.44) | ADRA2AADRA2BADRA2CMAPTMAPK8 | |
| SCHEMBL3633337 | 0.86 | ADRA2A (0.43) | ADRA2AADRA2BADRA2CMAPTMAPK8 | |
| SCHEMBL10713730 | 0.84 | ADRA2A (0.63) | ADRA2AADRA2BADRA2CMAPTPOLB | |
| SCHEMBL10713178 | 0.81 | MAPK8 (0.42) | ADRA2AADRA2BADRA2CMAPTMAPK8 | |
| SCHEMBL10715043 | 0.80 | MAPT (0.34) | MAPTPOLBALDH1A1HSD17B10TSHR | |
| SCHEMBL13118448 | 0.75 | ADRA2A (0.43) | ADRA2AADRA2BADRA2CMAPTMAPK8 | |
| SCHEMBL7849672 | 0.74 | POLB (0.46) | MAPTPOLBCYP3A4ALDH1A1HPGD | |
| SCHEMBL13861476 | 0.73 | MAPT (0.61) | MAPTMAPK8MAPK9MAPK10POLB | |
| SCHEMBL10710821 | 0.72 | CNR2 (0.42) | MAPTMAPK10ALDH1A1HSD17B10TSHR | |
| SCHEMBL7232358 | 0.71 | CYP3A4 (0.47) | POLBCYP3A4ACHEALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3940246-A | Sublimation transfer and isocyanate fixation of amino- or hydroxy-containing dyestuffs and transfer sheets therefor | CIBA-GEIGY AG (CH) | 1976-02-24 | — | — | US | claimed |
| US-4692461-A | PLANT PROTECTION | BAYER AKTIENGESELLSCHAFT (DE) | 1987-09-08 | — | — | US | disclosed |
| EP-0224140-A1 | Thienyl urea derivatives | BAYER AG (DE) | 1987-06-03 | — | — | EP | disclosed |
| US-4078886-A | Sublimation transfer and diisocyanate fixation of amino- or hydroxy-containing anthraquinone dyestuffs and transfer sheets thereof | CIBA-GEIGY AG (CH) | 1978-03-14 | — | — | US | disclosed |
| US-3958933-A | Process for the manufacture of fast dyeings on synthetic hydrophobic textile material | CIBA-GEIGY CORPORATION (US) | 1976-06-01 | — | — | US | disclosed |
| US-3940246-A | Sublimation transfer and isocyanate fixation of amino- or hydroxy-containing dyestuffs and transfer sheets therefor | CIBA-GEIGY AG (CH) | 1976-02-24 | — | — | US | disclosed |