SCHEMBL10715035

SCHEMBL10715035

BrC1CCCCCCC(Br)C(Br)CCC1Br

nearest known ligand 0.35

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.33
HSD17B10 Q99714 2/20 0.33
AR P10275 1/20 0.31
TSHR P16473 1/20 0.31
MAPK1 P28482 1/20 0.31
ATM Q13315 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
CES2 O00748 1/20 0.30
CES1 P23141 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9718773 0.96 ALDH1A1 (0.36) ALDH1A1HSD17B10ARTSHRMAPK1
SCHEMBL5881101 0.96
SCHEMBL12079166 0.96 ALDH1A1 (0.36) ALDH1A1HSD17B10TSHRCES2CES1
SCHEMBL6269441 0.96 ALDH1A1 (0.36) ALDH1A1HSD17B10TSHRCES2CES1
SCHEMBL13891938 0.96 ALDH1A1 (0.36) ALDH1A1HSD17B10TSHRCES2CES1
SCHEMBL7052054 0.91
SCHEMBL5376743 0.91
SCHEMBL5376738 0.91
SCHEMBL6900438 0.91
SCHEMBL989373 0.91

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0137916-B1 PROCESS FOR CONTROLLING PEARL DIMENSIONS IN THE PREPARATION OF EXPANDABLE STYRENE POLYMERS BY SUSPENSION POLYMERIZATION HÜLS AKTIENGESELLSCHAFT (DE) 1988-09-21 EP disclosed
US-4618468-A CONTROLLED MOLECULAR WEIGHT PROTECTIVE COLLOID CHEMISCHE WERKE HULS AKTIENGESELLSCHAFT (DE) 1986-10-21 US disclosed
EP-0137916-A2 Process for controlling pearl dimensions in the preparation of expandable styrene polymers by suspension polymerization HÜLS AKTIENGESELLSCHAFT (DE) 1985-04-24 EP disclosed