⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL786301 | 0.74 | HTT (0.31) | — | |
| SCHEMBL13082294 | 0.73 | — | — | |
| SCHEMBL4164685 | 0.73 | — | — | |
| SCHEMBL13058604 | 0.68 | ERBB2 (0.34) | — | |
| SCHEMBL7491398 | 0.68 | — | — | |
| SCHEMBL24363089 | 0.68 | NOTUM (0.33) | — | |
| SCHEMBL13075122 | 0.68 | PARP1 (0.37) | — | |
| SCHEMBL29512208 | 0.68 | USP8 (0.40) | — | |
| SCHEMBL363772 | 0.68 | — | — | |
| SCHEMBL31405648 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0116494-B1 | PYRIDAZINE DERIVATIVES WITH A PSYCHOTROPE ACTIVITY, PROCESS FOR THEIR PREPARATION, INTERMEDIATES AND MEDICINES CONTAINING THEM | SANOFI S.A. (FR) | 1988-01-27 | — | — | EP | claimed |
| EP-0116494-A1 | Pyridazine derivatives with a psychotrope activity, process for their preparation, intermediates and medicines containing them | SANOFI S.A. (FR) | 1984-08-22 | — | — | EP | claimed |
| EP-0116494-B1 | PYRIDAZINE DERIVATIVES WITH A PSYCHOTROPE ACTIVITY, PROCESS FOR THEIR PREPARATION, INTERMEDIATES AND MEDICINES CONTAINING THEM | SANOFI S.A. (FR) | 1988-01-27 | — | — | EP | disclosed |
| EP-0116494-A1 | Pyridazine derivatives with a psychotrope activity, process for their preparation, intermediates and medicines containing them | SANOFI S.A. (FR) | 1984-08-22 | — | — | EP | disclosed |