⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5700069 | 0.79 | — | — | |
| SCHEMBL11465936 | 0.78 | LMNA (0.43) | — | |
| SCHEMBL3765030 | 0.77 | — | — | |
| SCHEMBL970873 | 0.77 | — | — | |
| SCHEMBL12086447 | 0.75 | CYP11B1 (0.44) | — | |
| SCHEMBL29533314 | 0.74 | LRRK2 (0.46) | — | |
| SCHEMBL18611 | 0.74 | LRRK2 (0.46) | — | |
| SCHEMBL2108784 | 0.74 | CYP11B1 (0.43) | — | |
| SCHEMBL30320148 | 0.74 | PLCG1 (0.41) | — | |
| SCHEMBL167824 | 0.74 | PLCG1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 751 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119654312-A | Substituted tetrazolyl compounds useful as T cell activators | 百时美施贵宝公司 | 2025-03-18 | — | — | CN | claimed |
| CN-115974774-B | Preparation method and application of chloropicolinic acid | 利尔化学股份有限公司 | 2024-09-03 | — | — | CN | claimed |
| CN-116924979-A | Preparation method of 2-cyano-3-fluoropyridine | 阜新金特莱氟化学有限责任公司 | 2023-10-24 | — | — | CN | claimed |
| CN-115974774-A | Preparation method and application of chloropyridine formic acid | 利尔化学股份有限公司 | 2023-04-18 | — | — | CN | claimed |
| CN-110498767-A | The synthetic method of the chloro- 2- cyanopyridine of 3,5- bis- | CHONGQING MEDICAL & PHARMACEUTICAL COLLEGE | 2019-11-26 | — | — | CN | claimed |
| CN-209423360-U | It is a kind of for producing the mixer of four chloro- 2- cyanopyridines | 湖南比德生化科技股份有限公司 | 2019-09-24 | — | — | CN | claimed |
| CN-109092091-A | It is a kind of for producing the mixer of the chloro- 2- cyanopyridine of 3,4,5,6- tetra- | 湖南比德生化科技股份有限公司 | 2018-12-28 | — | — | CN | claimed |
| CN-109020882-A | The synthetic method of the chloro- 2- cyanopyridine of 3,5- bis- | 杭州华东医药集团浙江华义制药有限公司 | 2018-12-18 | — | — | CN | claimed |
| CN-207581700-U | A kind of liquid phase chlorination method process units of four chloro- 2- cyanopyridines | 南京大学 | 2018-07-06 | — | — | CN | claimed |
| CN-108114691-A | For the modified aluminas adsorbent of benzene in Adsorption wastewater from chemical industry | 北京益清源环保科技有限公司 | 2018-06-05 | — | — | CN | claimed |
| CN-103429082-B | Process for the preparation of 4-amino-3-chloro-5-fluoro-6-(substituted)picolinates | DOW AGROSCIENCES LLC | 2015-05-06 | — | — | CN | claimed |
| CN-103874685-A | Process for the preparation of 4-amino-3-chloro-5-fluoro-6- (substituted) pyridine-2-carboxylic acid esters | DOW AGROSCIENCES LLC | 2014-06-18 | — | — | CN | claimed |
| CN-103429082-A | Process for the preparation of 4-amino-3-chloro-5-fluoro-6-(substituted)picolinates | DOW AGROSCIENCES LLC | 2013-12-04 | — | — | CN | claimed |
| CN-102133523-B | Method for re-activating inactivated catalyst through catalytic chlorination of pyridine nitrile | UNIV XIANGTAN | 2012-11-14 | — | — | CN | claimed |
| CN-101906447-B | Method for producing 3,6-dichloropyrimidine-2-carboxylic acid by biocatalysis | NANJING HUAZHOU PHARMACEUTICAL | 2012-09-05 | — | — | CN | claimed |
| CN-102133523-A | Method for re-activating inactivated catalyst through catalytic chlorination of pyridine nitrile | UNIV XIANGTAN | 2011-07-27 | — | — | CN | claimed |
| CN-101906447-A | Method for producing 3,6-dichloropyrimidine-2-carboxylic acid by biocatalysis | NANJING NO 1 PESTICIDE CO LTD | 2010-12-08 | — | — | CN | claimed |
| EP-1569925-A1 | 2-SUBSTITUTED QUINAZOLIN-4-YLAMINE ANALOGUES AS CAPSAICIN RECEPTOR MODULATORS | NEUROGEN CORPORATION (US) | 2005-09-07 | — | — | EP | claimed |
| WO-2004055003-A1 | 2-SUBSTITUTED QUINAZOLIN-4-YLAMINE ANALOGUES AS CAPSAICIN RECEPTOR MODULATORS | NEUROGEN CORPORATION (US) | 2004-07-01 | — | — | WO | claimed |
| EP-0204535-B1 | N-FLUOROPYRIDINIUM SALT AND PROCESS FOR PREPARING SAME | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1992-08-19 | — | — | EP | claimed |