Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRS3 | P32247 | 3/20 | 0.68 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.44 |
| ▸ | AGXT | P21549 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | WDR5 | P61964 | 3/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | ATP4A | P20648 | 3/20 | 0.40 |
| ▸ | ATP4B | P51164 | 3/20 | 0.40 |
| ▸ | DDAH1 | O94760 | 2/20 | 0.40 |
| ▸ | ENGASE | Q8NFI3 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | ATP1A1 | P05023 | 2/20 | 0.40 |
| ▸ | ATP1B1 | P05026 | 2/20 | 0.40 |
| ▸ | ATP1A3 | P13637 | 2/20 | 0.40 |
| ▸ | ATP1B2 | P14415 | 2/20 | 0.40 |
| ▸ | ATP1A2 | P50993 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10578851 | 0.84 | BRS3 (0.74) | BRS3SHMT2KMT2AWDR5CYP2C9 | |
| Ufiprazole SCHEMBL1816535 | 0.81 | BRS3 (1.00) | BRS3KMT2AWDR5CYP2C9CYP1A2 | |
| Ufiprazole SCHEMBL29693729 | 0.81 | BRS3 (1.00) | BRS3KMT2AWDR5CYP2C9CYP1A2 | |
| Ufiprazole SCHEMBL662986 | 0.81 | BRS3 (0.84) | BRS3KMT2AWDR5CYP2C9CYP1A2 | |
| Ufiprazole SCHEMBL29455226 | 0.81 | BRS3 (0.84) | BRS3KMT2AWDR5CYP2C9CYP1A2 | |
| Ufiprazole SCHEMBL3180530 | 0.81 | BRS3 (0.76) | BRS3SHMT2KMT2AWDR5CYP2C9 | |
| SCHEMBL14648553 | 0.80 | BRS3 (0.69) | BRS3SHMT2AGXTKMT2AWDR5 | |
| Ufiprazole SCHEMBL7929368 | 0.80 | BRS3 (0.82) | BRS3KMT2AWDR5CYP2C9CYP1A2 | |
| Ufiprazole SCHEMBL31529606 | 0.80 | BRS3 (0.82) | BRS3KMT2AWDR5CYP2C9CYP1A2 | |
| SCHEMBL19974777 | 0.80 | BRS3 (0.66) | BRS3SHMT2AGXTKMT2AWDR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1987005296-A1 | 2-[(2-PYRIDYL)METHYLSULFINYL]THIENOIMIDAZOLES AND RELATED COMPOUNDS AS ANTIULCER AGENTS | PFIZER INC. (US) | 1987-09-11 | — | — | WO | disclosed |