SCHEMBL10716396

SCHEMBL10716396

Cc1cc(C(=O)O)c2c(c1C(=O)O)CC2

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.42
ACHE P22303 1/20 0.42
ALDH1A1 P00352 3/20 0.40
KDM4E B2RXH2 3/20 0.40
GAA P10253 1/20 0.40
HPGD P15428 1/20 0.40
HSD17B10 Q99714 1/20 0.40
MAPK1 P28482 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
NOTUM Q6P988 2/20 0.38
MAPT P10636 2/20 0.37
POLB P06746 2/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
PRNP P04156 1/20 0.36
PPARG P37231 1/20 0.36
HTT P42858 1/20 0.36
NCOA2 Q15596 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
RXFP1 Q9HBX9 1/20 0.36
NR2E3 Q9Y5X4 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL754115 0.81 CYP1A2 (0.39) ALDH1A1KDM4EHPGDHSD17B10SMN1; SMN2
SCHEMBL9338883 0.78 CYP3A4 (0.39) CYP3A4ACHEALDH1A1KDM4EGAA
SCHEMBL2529829 0.74 CYP3A4 (0.48) CYP3A4ACHEALDH1A1KDM4EGAA
SCHEMBL537616 0.72 CYP3A4 (0.47) CYP3A4ACHEALDH1A1KDM4EGAA
SCHEMBL29927238 0.72 CYP3A4 (0.47) CYP3A4ACHEALDH1A1KDM4EGAA
SCHEMBL3030086 0.72 CYP3A4 (0.47) CYP3A4ACHEALDH1A1KDM4EGAA
SCHEMBL9423558 0.72 CYP3A4 (0.42) CYP3A4ACHEALDH1A1KDM4EGAA
SCHEMBL31401770 0.72 CYP1A2 (0.56) CYP3A4ACHEALDH1A1KDM4EGAA
SCHEMBL19124079 0.72 GAA (0.42) ALDH1A1KDM4EGAAHPGDHSD17B10
SCHEMBL20558628 0.72 GAA (0.42) ALDH1A1KDM4EGAAHPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0146980-B1 PROCESS FOR FORMING FIXED IMAGES Océ-Nederland B.V. (NL) 1988-03-30 EP disclosed
EP-0146980-A1 Process for forming fixed images Océ-Nederland B.V. (NL) 1985-07-03 EP disclosed