SCHEMBL754115

SCHEMBL754115

O=C(O)c1cc(C(=O)O)c(C(=O)O)c2c1CC2

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.39
ALDH1A1 P00352 4/20 0.33
AKR1C3 P42330 3/20 0.33
ALOX15 P16050 1/20 0.33
AKR1C4 P17516 1/20 0.33
AKR1C2 P52895 1/20 0.33
AKR1C1 Q04828 1/20 0.33
HSD17B10 Q99714 3/20 0.32
KDM4E B2RXH2 2/20 0.32
HPGD P15428 2/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
MAPT P10636 1/20 0.32
GLA P06280 1/20 0.32
TSHR P16473 2/20 0.31
CYP2C9 P11712 2/20 0.31
CDC25A P30304 1/20 0.31
CDC25B P30305 1/20 0.31
LCK P06239 1/20 0.31
FYN P06241 1/20 0.31
ALOX12 P18054 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9338883 0.83 CYP3A4 (0.39) CYP1A2ALDH1A1AKR1C3ALOX15AKR1C4
SCHEMBL10716396 0.81 CYP3A4 (0.42) ALDH1A1HSD17B10KDM4EHPGDSMN1; SMN2
SCHEMBL338428 0.75 CYP1A2 (0.46) CYP1A2ALDH1A1AKR1C3ALOX15AKR1C4
SCHEMBL11217097 0.75 CA1 (0.47) CYP1A2KDM4EGLATSHRCYP2C9
Mellitic Acid SCHEMBL11153446 0.75 ALDH1A1 (0.43) CYP1A2ALDH1A1AKR1C3ALOX15AKR1C4
Benzenepentacarboxylic Acid SCHEMBL432193 0.75 ALDH1A1 (0.43) CYP1A2ALDH1A1AKR1C3ALOX15AKR1C4
SCHEMBL3034094 0.74 CYP1A2 (0.38) CYP1A2ALDH1A1KDM4EMAPTTSHR
SCHEMBL12478008 0.74 ACMSD (0.41) KDM4EMAPT
SCHEMBL22802151 0.73 TSHR (0.43) CYP1A2ALDH1A1AKR1C3ALOX15AKR1C4
SCHEMBL17907195 0.73 CYP1A2 (0.50) CYP1A2ALDH1A1AKR1C3ALOX15HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8654290-B2 Liquid crystal display device SHARP KABUSHIKI KAISHA (JP) 2014-02-18 US disclosed
EP-2431798-A1 LIQUID CRYSTAL DISPLAY DEVICE Sharp Kabushiki Kaisha (JP) 2012-03-21 EP disclosed
US-7790248-B2 Active matrix type liquid crystal display apparatus HITACHI, LTD. (JP) 2010-09-07 US disclosed
US-7615260-B2 Active-matrix liquid crystal display HITACHI, LTD. (JP) 2009-11-10 US disclosed
US-20050012884-A1 Active-matrix liquid crystal display IPS ALPHA SUPPORT CO., LTD. (JP) 2005-01-20 US disclosed
EP-0806698-B1 In-plane switching-mode active-matrix liquid crystal display HITACHI LTD (JP) 2005-01-12 EP disclosed
US-6756089-B2 MULTILAYER; POLYAMIDEIMIDE COPOLYMER HITACHI, LTD. (JP) 2004-06-29 US disclosed
US-20010046569-A1 Active-matrix liquid crystal display IPS ALPHA SUPPORT CO., LTD. (JP) 2001-11-29 US disclosed
US-6242060-B1 MULTILAYER HITACHI, LTD. (JP) 2001-06-05 US disclosed
US-5928733-A Active-matrix liquid crystal display HITACHI, LTD. (JP) 1999-07-27 US disclosed
EP-0806698-A1 Active-matrix liquid crystal display HITACHI, LTD. (JP) 1997-11-12 EP disclosed
US-4012555-A Self-bonding varnish for magnet wires comprising a combination of a polyalkylenetrimellitate imide and a polyalkylenetrimellitate ester imide STANDARD OIL COMPANY (INDIANA) (US) 1977-03-15 US disclosed