Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 4/20 | 0.55 |
| ▸ | BACE1 | P56817 | 4/20 | 0.55 |
| ▸ | LCK | P06239 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10716610 | 1.00 | GSK3B (0.55) | GSK3BBACE1LCKHTTNPC1 | |
| SCHEMBL10716623 | 1.00 | GSK3B (0.55) | GSK3BBACE1LCKHTTNPC1 | |
| SCHEMBL28463122 | 0.88 | HTT (0.58) | HTTLMNAKMT2A | |
| SCHEMBL28452117 | 0.83 | GSK3B (0.55) | GSK3BBACE1LCKNPC1RAB9A | |
| SCHEMBL10871502 | 0.81 | GSK3B (0.58) | GSK3BBACE1LCKNPC1RAB9A | |
| SCHEMBL20024692 | 0.78 | LCK (0.77) | GSK3BBACE1LCKNPC1RAB9A | |
| SCHEMBL14786203 | 0.78 | LCK (0.77) | GSK3BBACE1LCKNPC1RAB9A | |
| SCHEMBL21841016 | 0.77 | LCK (0.55) | GSK3BBACE1LCKNPC1RAB9A | |
| SCHEMBL8913590 | 0.77 | LCK (0.81) | GSK3BBACE1LCKNPC1RAB9A | |
| SCHEMBL8913578 | 0.77 | LCK (0.81) | GSK3BBACE1LCKNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-62004269-A | — | — | None | — | — | JP | disclosed |
| JP-62004240-A | — | — | None | — | — | JP | disclosed |
| JP-S624269-A | (+)-LATIFINE AND PRODUCTION THEREOF | KAWAKEN FINE CHEM CO LTD | 1987-01-10 | — | — | JP | disclosed |
| JP-S624240-A | OPTICALLY ACTIVE ALLYL ALCOHOL COMPOUND | KAWAKEN FINE CHEM CO LTD | 1987-01-10 | — | — | JP | disclosed |