Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 1/20 | 0.55 |
| ▸ | GSK3B | P49841 | 4/20 | 0.53 |
| ▸ | BACE1 | P56817 | 4/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 2/20 | 0.49 |
| ▸ | PPARA | Q07869 | 2/20 | 0.49 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.49 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.49 |
| ▸ | PPARD | Q03181 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
| ▸ | APP | P05067 | 1/20 | 0.48 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10871502 | 0.83 | GSK3B (0.58) | LCKGSK3BBACE1NPC1RAB9A | |
| SCHEMBL7923406 | 0.82 | MEN1 (0.49) | CYP1A2PPARGPPARAPPARDMAOB | |
| SCHEMBL7923413 | 0.82 | MEN1 (0.49) | CYP1A2PPARGPPARAPPARDMAOB | |
| SCHEMBL20024692 | 0.77 | LCK (0.77) | LCKGSK3BBACE1NPC1RAB9A | |
| SCHEMBL14786203 | 0.77 | LCK (0.77) | LCKGSK3BBACE1NPC1RAB9A | |
| SCHEMBL10716618 | 0.77 | GSK3B (0.55) | LCKGSK3BBACE1NPC1RAB9A | |
| SCHEMBL28452117 | 0.77 | GSK3B (0.55) | LCKGSK3BBACE1NPC1RAB9A | |
| SCHEMBL10716610 | 0.77 | GSK3B (0.55) | LCKGSK3BBACE1NPC1RAB9A | |
| SCHEMBL10716623 | 0.77 | GSK3B (0.55) | LCKGSK3BBACE1NPC1RAB9A | |
| SCHEMBL8913578 | 0.76 | LCK (0.81) | LCKGSK3BBACE1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2768805-B1 | (HETERO)ARYL CYCLOPROPYLAMINE COMPOUNDS AS LSD1 INHIBITORS | ORYZON GENOMICS SA (ES) | 2020-03-25 | — | — | EP | disclosed |