Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.49 |
| ▸ | PLAU | P00749 | 2/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.47 |
| ▸ | F12 | P00748 | 1/20 | 0.47 |
| ▸ | NCF1 | P14598 | 1/20 | 0.47 |
| ▸ | NOS3 | P29474 | 1/20 | 0.47 |
| ▸ | NOS1 | P29475 | 1/20 | 0.47 |
| ▸ | NOS2 | P35228 | 1/20 | 0.47 |
| ▸ | BACE1 | P56817 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | PLG | P00747 | 1/20 | 0.40 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CFTR | P13569 | 1/20 | 0.39 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24170548 | 0.84 | FDPS (0.51) | FDPSPLAUCYP2A6F12NCF1 | |
| SCHEMBL4479184 | 0.80 | CYP2A6 (0.55) | FDPSPLAUCYP2A6F12NCF1 | |
| SCHEMBL6175758 | 0.79 | EGFR (0.56) | FDPSPLAUCYP2A6F12NCF1 | |
| SCHEMBL34467229 | 0.79 | EGFR (0.56) | FDPSPLAUCYP2A6F12NCF1 | |
| SCHEMBL1133566 | 0.76 | FDPS (0.56) | FDPSPLAUCYP2A6F12NCF1 | |
| SCHEMBL27931662 | 0.76 | FDPS (0.51) | FDPSPLAUCYP2A6F12NCF1 | |
| SCHEMBL159146 | 0.76 | PLAU (0.55) | FDPSPLAUCYP2A6F12NCF1 | |
| Hydrazine SCHEMBL5804370 | 0.74 | PLAU (0.53) | FDPSPLAUCYP2A6F12NCF1 | |
| SCHEMBL1921849 | 0.73 | ABCG2 (0.53) | FDPSPLAUCYP2A6F12NCF1 | |
| SCHEMBL2622211 | 0.72 | CYP2A6 (0.50) | FDPSPLAUCYP2A6F12NCF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0224842-A2 | Pyrazolesulfonamide derivative, process for its production and herbicide containing it | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1987-06-10 | — | — | EP | disclosed |