SCHEMBL107178

SCHEMBL107178

CC(O)C(=O)Cc1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.55
CES1 P23141 2/20 0.54
CES2 O00748 1/20 0.54
AKR1B1 P15121 1/20 0.54
PSMB8 P28062 1/20 0.47
PSMB5 P28074 1/20 0.47
POLB P06746 1/20 0.47
HDAC8 Q9BY41 3/20 0.47
HDAC6 Q9UBN7 3/20 0.47
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
CNR2 P34972 2/20 0.46
NPC1 O15118 1/20 0.46
RAB9A P51151 1/20 0.46
FNTA P49354 1/20 0.45
FNTB P49356 1/20 0.45
HDAC3 O15379 2/20 0.45
HDAC4 P56524 2/20 0.45
HDAC1 Q13547 2/20 0.45
HDAC7 Q8WUI4 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4725179 1.00 TSHR (0.55) TSHRCES1CES2AKR1B1PSMB8
Butanone SCHEMBL8113506 0.91 TSHR (0.47) TSHRCES1CES2AKR1B1PSMB8
SCHEMBL331007 0.84 TSHR (0.57) TSHRCES1CES2AKR1B1POLB
SCHEMBL106236 0.83 TSHR (0.52) TSHRCES1CES2AKR1B1PSMB8
SCHEMBL1426064 0.82 CES1 (0.58) TSHRCES1CES2AKR1B1POLB
SCHEMBL7268724 0.82 CES1 (0.58) TSHRCES1CES2AKR1B1HDAC8
SCHEMBL5247831 0.81 TSHR (0.53) TSHRCES1CES2AKR1B1POLB
SCHEMBL2334514 0.81 AKR1B1 (0.58) TSHRCES1CES2AKR1B1POLB
SCHEMBL8203182 0.81 TSHR (0.53) TSHRCES1CES2AKR1B1POLB
SCHEMBL108145 0.81 CA2 (0.54) NPC1RAB9AFNTAFNTB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 138 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2463374-A2 Isolated alcohol dehydrogenase enzymes and uses thereof Bio Architecture Lab, Inc. (US) 2012-06-13 EP claimed
EP-2195440-A2 BIOFUEL PRODUCTION Bio Architecture Lab, Inc. (US) 2010-06-16 EP claimed
US-20090155873-A1 BIOFUEL PRODUCTION BIO ARCHITECTURE LAB, INC. (US) 2009-06-18 US claimed
US-20090139134-A1 BIOFUEL PRODUCTION BIO ARCHITECTURE LAB, INC. (US) 2009-06-04 US claimed
WO-2009046375-A2 BIOFUEL PRODUCTION BIO ARCHITECTURE LAB, INC. (US) 2009-04-09 WO claimed
WO-2009046370-A2 BIOFUEL PRODUCTION BIO ARCHITECTURE LAB, INC. (US) 2009-04-09 WO claimed
EP-3230463-B2 RAPID PRETREATMENT APALTA PATENTS OUE (EE) 2025-07-16 EP disclosed
US-20250135459-A1 Tray Device ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2025-05-01 US disclosed
US-20240425893-A1 RAPID PRETREATMENT Apalta Patents OÜ (EE) 2024-12-26 US disclosed
US-20240368001-A1 SALT RECOVERY SOLUTION AND PROCESSES OF USE THEREOF AQUAFORTUS TECHNOLOGIES LIMITED (NZ) 2024-11-07 US disclosed
US-12054761-B2 Rapid pretreatment Apalta Patents OÜ (EE) 2024-08-06 US disclosed
US-11987506-B2 Salt recovery solution and processes of use thereof AQUAFORTUS TECHNOLOGIES LIMITED (NZ) 2024-05-21 US disclosed
US-11821047-B2 High pressure zone formation for pretreatment Apalta Patent OÜ (EE) 2023-11-21 US disclosed
EP-0552698-B1 A method of making a coated abrasive article MINNESOTA MINING & MFG (US) 1995-12-06 EP disclosed
US-5368618-A Method of making a coated abrasive article MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1994-11-29 US disclosed
EP-0552698-A2 A method of making a coated abrasive article MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-07-28 EP disclosed
US-5128387-A Extensible and pasteurizable radiation curable coating for metal BORDEN, INC. (US) 1992-07-07 US disclosed
EP-0248614-A1 Preparation of 3-hydroxy-3-phenylbutan-2-one AMERICAN HOME PRODUCTS CORPORATION (US) 1987-12-09 EP disclosed
US-4704475-A GRIGNARD REACTION AMERICAN HOME PRODUCTS CORPORATION (DEL.) (US) 1987-11-03 US disclosed
US-4251622-A CONTAINING A DYE, AN ARYL KETONE SENSITIZER, AND AN N-SUBSTITUTED POLYAMIDE OR A VINYL ACETATE POLYMER OF HIGH MOLECULAR WEIGHT NIPPON PAINT CO., LTD. (JP) 1981-02-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090139134-A1 BIOFUEL PRODUCTION MGAM, DCXR, MANBA TSHR 3426/4885CES1 73/4885CES2 60/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.