Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | CCR3 | P51677 | 3/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.39 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | GRN | P28799 | 1/20 | 0.38 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.38 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9825374 | 0.85 | ABCB1 (0.50) | — | |
| SCHEMBL10718302 | 0.82 | POLB (0.51) | SMN1; SMN2MEN1KMT2ANPC1RAB9A | |
| SCHEMBL9714242 | 0.80 | CYP3A4 (0.58) | HPGDSMN1; SMN2 | |
| SCHEMBL9825031 | 0.79 | KMT2A (0.42) | HPGDSMN1; SMN2MEN1KMT2A | |
| SCHEMBL9825501 | 0.79 | HPGD (0.38) | HPGDGRNSORT1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL8177913 | 0.79 | CYP3A4 (0.57) | HPGDSMN1; SMN2 | |
| SCHEMBL9825414 | 0.77 | CYP2C9 (0.48) | HPGDS1PR3GRNSORT1MEN1 | |
| SCHEMBL10718578 | 0.77 | ABCB1 (0.45) | SMN1; SMN2NPC1RAB9A | |
| SCHEMBL5064132 | 0.75 | ABCB1 (0.67) | HPGDSMN1; SMN2 | |
| SCHEMBL9877218 | 0.74 | POLB (0.58) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0236618-A2 | Insecticidal N'-substituted-N,N'-diacylhydrazines | ROHM AND HAAS COMPANY (US) | 1987-09-16 | — | — | EP | disclosed |