Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.38 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9557839 | 0.82 | HSD11B1 (0.40) | KMT2AMEN1ALDH1A1CYP2C9CYP1A2 | |
| SCHEMBL9557984 | 0.80 | L3MBTL1 (0.41) | KMT2AMEN1ALDH1A1MAPTCRHBP | |
| SCHEMBL10718172 | 0.79 | HPGD (0.42) | KMT2AMEN1SMN1; SMN2HPGD | |
| SCHEMBL9825414 | 0.78 | CYP2C9 (0.48) | KMT2AMEN1CYP2C9CYP1A2CYP2C19 | |
| SCHEMBL9496095 | 0.78 | MEN1 (0.51) | KMT2AMEN1CYP2C9CYP1A2CYP2C19 | |
| SCHEMBL9877218 | 0.74 | POLB (0.58) | ALDH1A1CYP2C9CYP3A4LMNAPOLB | |
| SCHEMBL10718302 | 0.71 | POLB (0.51) | KMT2AMEN1ALDH1A1CYP2C9CYP3A4 | |
| SCHEMBL9825501 | 0.70 | HPGD (0.38) | KMT2AMEN1ALDH1A1CYP2C9CYP1A2 | |
| SCHEMBL9825783 | 0.70 | POLB (0.52) | ALDH1A1CYP2C9CYP3A4LMNAPOLB | |
| SCHEMBL9241810 | 0.69 | POLB (0.71) | KMT2AMEN1CYP2C9CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0236618-B1 | INSECTICIDAL N'-SUBSTITUTED-N,N'-DIACYLHYDRAZINES | ROHM AND HAAS COMPANY (US) | 1991-02-27 | — | — | EP | disclosed |
| US-4985461-A | Insecticidal N'-substituted-N,N'-diacylhydrazines | ROHM AND HAAS COMPANY (US) | 1991-01-15 | — | — | US | disclosed |
| EP-0236618-A2 | Insecticidal N'-substituted-N,N'-diacylhydrazines | ROHM AND HAAS COMPANY (US) | 1987-09-16 | — | — | EP | disclosed |