Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CRHBP | P24387 | 2/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10721628 | 0.88 | ABCB1 (0.53) | ABCB1CYP3A4 | |
| SCHEMBL5057389 | 0.81 | ABCB1 (0.65) | ABCB1CYP3A4SMN1; SMN2 | |
| SCHEMBL10721229 | 0.80 | ALDH1A1 (0.47) | SMN1; SMN2LMNAPOLBMEN1KMT2A | |
| SCHEMBL2682600 | 0.79 | ABCB1 (0.52) | ABCB1CYP3A4 | |
| SCHEMBL2682676 | 0.79 | ABCB1 (0.52) | ABCB1CYP3A4 | |
| SCHEMBL19946415 | 0.79 | ABCB1 (0.52) | ABCB1CYP3A4 | |
| SCHEMBL17600750 | 0.78 | ABCB1 (0.36) | ABCB1CYP3A4SMN1; SMN2LMNAMEN1 | |
| SCHEMBL17600752 | 0.78 | ABCB1 (0.36) | ABCB1CYP3A4SMN1; SMN2LMNAMEN1 | |
| SCHEMBL28789040 | 0.75 | ABCB1 (0.46) | ABCB1CYP3A4SMN1; SMN2 | |
| SCHEMBL17600858 | 0.74 | ABCB1 (0.40) | ABCB1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0236618-A2 | Insecticidal N'-substituted-N,N'-diacylhydrazines | ROHM AND HAAS COMPANY (US) | 1987-09-16 | — | — | EP | disclosed |