Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 8/20 | 0.40 |
| ▸ | HTR2A | P28223 | 6/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | HRH2 | P25021 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | STAT3 | P40763 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9235139 | 0.99 | MCHR1 (0.41) | MCHR1HTR2ACHRM1L3MBTL1RAB9A | |
| SCHEMBL9240434 | 0.99 | MCHR1 (0.41) | MCHR1HTR2ACHRM1L3MBTL1RAB9A | |
| SCHEMBL9239297 | 0.99 | MCHR1 (0.41) | MCHR1HTR2ACHRM1L3MBTL1RAB9A | |
| SCHEMBL9240875 | 0.99 | MCHR1 (0.41) | MCHR1HTR2ACHRM1L3MBTL1RAB9A | |
| SCHEMBL9237634 | 0.99 | MCHR1 (0.41) | MCHR1HTR2ACHRM1L3MBTL1RAB9A | |
| SCHEMBL9240272 | 0.99 | MCHR1 (0.41) | MCHR1HTR2ACHRM1L3MBTL1RAB9A | |
| SCHEMBL9236018 | 0.99 | MCHR1 (0.41) | MCHR1HTR2ACHRM1L3MBTL1RAB9A | |
| SCHEMBL9240385 | 0.99 | MCHR1 (0.41) | MCHR1HTR2ACHRM1L3MBTL1RAB9A | |
| SCHEMBL9630624 | 0.88 | RAB9A (0.49) | L3MBTL1RAB9AMAPTCASP3SENP8 | |
| SCHEMBL9630649 | 0.88 | RAB9A (0.49) | L3MBTL1RAB9AMAPTCASP3SENP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0220297-A1 | NITROGEN-CONTAINING HETEROCYCLES. | MERCK PATENT GMBH (DE) | 1987-05-06 | — | — | EP | disclosed |
| WO-1986006373-A1 | NITROGEN-CONTAINING HETEROCYCLES | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1986-11-06 | — | — | WO | disclosed |