Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 9/20 | 0.46 |
| ▸ | REN | P00797 | 4/20 | 0.46 |
| ▸ | F2 | P00734 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | PEPD | P12955 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | THPO | P40225 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.42 |
| ▸ | XPNPEP2 | O43895 | 1/20 | 0.39 |
| ▸ | TMPRSS11D | O60235 | 1/20 | 0.39 |
| ▸ | F10 | P00742 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10719620 | 0.91 | ACE (0.57) | ACERENF2LMNAKDM4E | |
| SCHEMBL10653264 | 0.81 | ACE (0.51) | ACERENF2LMNAKDM4E | |
| SCHEMBL10653271 | 0.81 | ACE (0.51) | ACERENF2LMNAKDM4E | |
| SCHEMBL29592022 | 0.79 | ACE (0.47) | ACERENF2LMNAKDM4E | |
| SCHEMBL29630367 | 0.78 | ACE (0.52) | ACERENF2LMNAKDM4E | |
| SCHEMBL7271779 | 0.78 | ACE (0.52) | ACERENF2LMNAKDM4E | |
| SCHEMBL10402260 | 0.78 | MMP2 (0.53) | ACEF2LMNALTA4HTMPRSS11D | |
| SCHEMBL30062556 | 0.78 | ACE (0.46) | ACERENF2LMNAKDM4E | |
| SCHEMBL6439118 | 0.77 | ACE (0.46) | ACERENF2LMNAKDM4E | |
| SCHEMBL6439113 | 0.77 | ACE (0.46) | ACERENF2LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-62072698-A | — | — | None | — | — | JP | disclosed |
| JP-S6272698-A | AMINO ACID DERIVATIVE AND HYPOTENSOR CONTAINING SAID DERIVATIVE | AJINOMOTO CO INC | 1987-04-03 | — | — | JP | disclosed |