Biphenyl

Biphenyl

SCHEMBL1072001

C[Sn]C.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.69

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.69
SLC22A2 O15244 1/20 0.50
SLC22A1 O15245 1/20 0.50
SLC22A3 O75751 1/20 0.50
SLC6A4 P31645 1/20 0.50
TAAR1 Q96RJ0 3/20 0.47
CYP1A2 P05177 2/20 0.47
MAPK1 P28482 2/20 0.47
CYP3A4 P08684 1/20 0.47
HSD17B10 Q99714 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
NOTUM Q6P988 1/20 0.47
MMP3 P08254 1/20 0.47
BCL2L1 Q07817 1/20 0.47
SMN1; SMN2 Q16637 2/20 0.43
CYP1A1 P04798 1/20 0.43
CYP1B1 Q16678 1/20 0.43
MAPT P10636 1/20 0.43
ATM Q13315 1/20 0.43
NPC1 O15118 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biphenyl SCHEMBL653702 0.84 ALDH1A1 (0.82) ALDH1A1SLC22A2SLC22A1SLC22A3SLC6A4
SCHEMBL29560186 0.83 ALDH1A1 (1.00) ALDH1A1SLC22A2SLC22A1SLC22A3SLC6A4
SCHEMBL30108088 0.83 ALDH1A1 (1.00) ALDH1A1SLC22A2SLC22A1SLC22A3SLC6A4
SCHEMBL30629023 0.83 ALDH1A1 (1.00) ALDH1A1SLC22A2SLC22A1SLC22A3SLC6A4
Biphenyl SCHEMBL2548048 0.83 ALDH1A1 (1.00) ALDH1A1SLC22A2SLC22A1SLC22A3SLC6A4
Biphenyl SCHEMBL28890607 0.83 ALDH1A1 (1.00) ALDH1A1SLC22A2SLC22A1SLC22A3SLC6A4
Biphenyl SCHEMBL164 0.83 ALDH1A1 (1.00) ALDH1A1SLC22A2SLC22A1SLC22A3SLC6A4
Biphenyl SCHEMBL4002609 0.83 ALDH1A1 (1.00) ALDH1A1SLC22A2SLC22A1SLC22A3SLC6A4
Biphenyl SCHEMBL29008551 0.83 ALDH1A1 (1.00) ALDH1A1SLC22A2SLC22A1SLC22A3SLC6A4
Biphenyl SCHEMBL1358618 0.83 ALDH1A1 (1.00) ALDH1A1SLC22A2SLC22A1SLC22A3SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104341256-A Low-cost and environment-friendly synthesis method of biphenyl derivatives HARBIN INST TECH WEIHAI 2015-02-11 CN claimed
CN-104262234-A Preparation method of biphenyl derivatives HARBIN INST TECH WEIHAI 2015-01-07 CN claimed
CN-104211559-A Preparation method of tetramethylbiphenyl isomers HARBIN INST TECH WEIHAI 2014-12-17 CN claimed
EP-2578626-B1 RUBBER COMPOSITION FOR TIRE INSULATIONS AND TIRE USING SAME SUMITOMO RUBBER IND (JP) 2016-03-30 EP disclosed
US-8993666-B2 Rubber composition for insulation of tire and tire using same SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2015-03-31 US disclosed
CN-104341256-A Low-cost and environment-friendly synthesis method of biphenyl derivatives HARBIN INST TECH WEIHAI 2015-02-11 CN disclosed
CN-104262234-A Preparation method of biphenyl derivatives HARBIN INST TECH WEIHAI 2015-01-07 CN disclosed
CN-104211559-A Preparation method of tetramethylbiphenyl isomers HARBIN INST TECH WEIHAI 2014-12-17 CN disclosed
US-8674015-B2 Rubber composition for sidewall and tire having sidewall using thereof, and rubber composition for clinch and tire having clinch using thereof SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2014-03-18 US disclosed
US-8674014-B2 Rubber composition for sidewall and tire having sidewall using thereof, and rubber composition for clinch and tire having clinch using thereof SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2014-03-18 US disclosed
US-20130137807-A1 RUBBER COMPOSITION FOR INSULATION OF TIRE AND TIRE USING SAME SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2013-05-30 US disclosed
EP-2153965-B1 Method for manufacturing pneumatic tire SUMITOMO RUBBER IND (JP) 2011-07-20 EP disclosed
US-20110094649-A1 RUBBER COMPOSITION FOR SIDEWALL AND TIRE HAVING SIDEWALL USING THEREOF, AND RUBBER COMPOSITION FOR CLINCH AND TIRE HAVING CLINCH USING THEREOF SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2011-04-28 US disclosed
EP-2159074-B1 Rubber composition for cap tread and tire having cap tread comprising the same SUMITOMO RUBBER IND (JP) 2011-01-19 EP disclosed
US-20100224299-A1 RUBBER COMPOSITION FOR TIRE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2010-09-09 US disclosed
US-20100227955-A1 RUBBER COMPOSITION FOR BREAKER TOPPING SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2010-09-09 US disclosed
EP-2159074-A1 Rubber composition for cap tread and tire having cap tread comprising the same SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2010-03-03 EP disclosed
EP-2153965-A1 Method for manufacturing pneumatic tire SUMITOMO RUBBER INDUSTRIES LTD. (JP) 2010-02-17 EP disclosed
US-20100036019-A1 RUBBER COMPOSITION FOR CAP TREAD AND TIRE HAVING CAP TREAD COMPRISING THE SAME SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2010-02-11 US disclosed
US-20100032078-A1 METHOD FOR MANUFACTURING PNEUMATIC TIRE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2010-02-11 US disclosed