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SCHEMBL10720656

SCHEMBL10720656

CCC(C)[C@@H](CO)NC(=O)CC(O)C(CC(C)C)NC(=O)[C@H](Cc1cscn1)NC(=O)[C@H](Cc1cccc2ccccc12)NC(=O)OCc1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ REN P00797 18/20 0.56
▸ CTSB P07858 1/20 0.49
▸ CTSK P43235 1/20 0.49
▸ CTSD P07339 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10720663 1.00 REN (0.56) RENCTSBCTSKCTSD
SCHEMBL10720537 0.95 REN (0.50) RENCTSBCTSK
SCHEMBL10720527 0.95 REN (0.50) RENCTSBCTSK
SCHEMBL10722802 0.93 REN (0.50) RENCTSBCTSK
SCHEMBL10722797 0.93 REN (0.50) RENCTSBCTSK
SCHEMBL11018235 0.92 REN (0.47) RENCTSBCTSKCTSD
SCHEMBL11018251 0.92 REN (0.47) RENCTSBCTSKCTSD
SCHEMBL10724514 0.92 REN (0.57) RENCTSBCTSKCTSD
SCHEMBL10724503 0.92 REN (0.57) RENCTSBCTSKCTSD
SCHEMBL10722729 0.92 REN (0.51) REN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4698329-A HYPOTENSIVE AGENTS SANKYO COMPANY, LIMITED (JP) 1987-10-06 — — US claimed
EP-0152255-A2 New renin-inhibitory peptides and their use SANKYO COMPANY LIMITED (JP) 1985-08-21 — — EP claimed
US-4698329-A HYPOTENSIVE AGENTS SANKYO COMPANY, LIMITED (JP) 1987-10-06 — — US disclosed
EP-0152255-A2 New renin-inhibitory peptides and their use SANKYO COMPANY LIMITED (JP) 1985-08-21 — — EP disclosed
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