SCHEMBL10720730

SCHEMBL10720730

CC(C)C[C@H](NC(=O)C(Cc1cscn1)NC(=O)[C@H](Cc1cccc2ccccc12)NC(=O)OCc1ccccc1)[C@@H](O)CC(=O)NCCc1ccccn1

nearest known ligand 0.56

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ REN P00797 20/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10720727 1.00 REN (0.56) REN
SCHEMBL10722966 0.94 REN (0.58) REN
SCHEMBL10722970 0.94 REN (0.58) REN
SCHEMBL10724959 0.92 REN (0.58) REN
SCHEMBL10724951 0.92 REN (0.58) REN
SCHEMBL10720941 0.90 REN (0.57) REN
SCHEMBL10720950 0.90 REN (0.57) REN
SCHEMBL10721038 0.90 REN (0.57) REN
SCHEMBL10721033 0.90 REN (0.57) REN
SCHEMBL10720746 0.89 REN (0.52) REN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4698329-A HYPOTENSIVE AGENTS SANKYO COMPANY, LIMITED (JP) 1987-10-06 — — US disclosed
EP-0152255-A2 New renin-inhibitory peptides and their use SANKYO COMPANY LIMITED (JP) 1985-08-21 — — EP disclosed
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