Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.72 |
| ▸ | PTGFR | P43088 | 3/20 | 0.66 |
| ▸ | TBXA2R | P21731 | 6/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.64 |
| ▸ | LMNA | P02545 | 5/20 | 0.64 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.64 |
| ▸ | SLCO2A1 | Q92959 | 2/20 | 0.64 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.64 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.64 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.64 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 4/20 | 0.56 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.56 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.53 |
| ▸ | PTGIR | P43119 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.53 |
| ▸ | ESR1 | P03372 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25710278 | 0.99 | MEN1 (0.73) | MEN1KMT2APTGFRTBXA2RALDH1A1 | |
| SCHEMBL22168569 | 0.99 | MEN1 (0.73) | MEN1KMT2APTGFRTBXA2RALDH1A1 | |
| SCHEMBL2512105 | 0.99 | MEN1 (0.73) | MEN1KMT2APTGFRTBXA2RALDH1A1 | |
| SCHEMBL2512107 | 0.99 | MEN1 (0.73) | MEN1KMT2APTGFRTBXA2RALDH1A1 | |
| SCHEMBL34165 | 0.99 | MEN1 (0.73) | MEN1KMT2APTGFRTBXA2RALDH1A1 | |
| SCHEMBL24726792 | 0.99 | MEN1 (0.73) | MEN1KMT2APTGFRTBXA2RALDH1A1 | |
| SCHEMBL9037070 | 0.93 | MEN1 (0.65) | MEN1KMT2APTGFRTBXA2RALDH1A1 | |
| Imidazole SCHEMBL10918367 | 0.88 | MEN1 (0.59) | MEN1KMT2APTGFRTBXA2RALDH1A1 | |
| SCHEMBL1782277 | 0.86 | MEN1 (0.58) | MEN1KMT2APTGFRTBXA2RALDH1A1 | |
| SCHEMBL24855289 | 0.86 | MEN1 (0.55) | MEN1KMT2APTGFRTBXA2RALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0223844-A1 | COMPOUNDS AND METHODS USEFUL FOR THE SYNTHESIS OF THROMBOXANE A 2? | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 1987-06-03 | — | — | EP | disclosed |
| WO-1986007058-A1 | COMPOUNDS AND METHODS USEFUL FOR THE SYNTHESIS OF THROMBOXANE A2 | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF (US) | 1986-12-04 | — | — | WO | disclosed |