Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.73 |
| ▸ | PTGFR | P43088 | 3/20 | 0.67 |
| ▸ | TBXA2R | P21731 | 6/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.65 |
| ▸ | LMNA | P02545 | 5/20 | 0.65 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.65 |
| ▸ | SLCO2A1 | Q92959 | 2/20 | 0.65 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.65 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.65 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.65 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 4/20 | 0.57 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.57 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.54 |
| ▸ | PTGIR | P43119 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.54 |
| ▸ | ESR1 | P03372 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2512105 | 1.00 | MEN1 (0.73) | MEN1KMT2APTGFRTBXA2RALDH1A1 | |
| SCHEMBL25710278 | 1.00 | MEN1 (0.73) | MEN1KMT2APTGFRTBXA2RALDH1A1 | |
| SCHEMBL22168569 | 1.00 | MEN1 (0.73) | MEN1KMT2APTGFRTBXA2RALDH1A1 | |
| SCHEMBL34165 | 1.00 | MEN1 (0.73) | MEN1KMT2APTGFRTBXA2RALDH1A1 | |
| SCHEMBL2512107 | 1.00 | MEN1 (0.73) | MEN1KMT2APTGFRTBXA2RALDH1A1 | |
| SCHEMBL10721021 | 0.99 | MEN1 (0.72) | MEN1KMT2APTGFRTBXA2RALDH1A1 | |
| SCHEMBL9037070 | 0.93 | MEN1 (0.65) | MEN1KMT2APTGFRTBXA2RALDH1A1 | |
| Imidazole SCHEMBL10918367 | 0.89 | MEN1 (0.59) | MEN1KMT2APTGFRTBXA2RALDH1A1 | |
| SCHEMBL1782277 | 0.87 | MEN1 (0.58) | MEN1KMT2APTGFRTBXA2RALDH1A1 | |
| SCHEMBL24855289 | 0.87 | MEN1 (0.55) | MEN1KMT2APTGFRTBXA2RALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220281797-A1 | KEY INTERMEDIATE FOR SYNTHESIS OF PROSTAGLANDIN COMPOUND AND PREPARATION METHOD THEREOF | SHENZHEN CATALYS TECHNOLOGY CO., LTD (CN) | 2022-09-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220281797-A1 | KEY INTERMEDIATE FOR SYNTHESIS OF PROSTAGLANDIN COMPOUND AND PREPARATION METHOD THEREOF | PTGES, PTGIS, PTGES2 | MEN1 3136/4885KMT2A 4072/4885PTGFR 8/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.