Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.49 |
| ▸ | PLK1 | P53350 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.45 |
| ▸ | TAOK3 | Q9H2K8 | 1/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.44 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.44 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8177791 | 0.88 | POLB (0.56) | HDAC1HDAC6HDAC3HDAC7HDAC8 | |
| SCHEMBL9825038 | 0.80 | POLB (0.50) | HPGDHDAC1HDAC6POLBCYP3A4 | |
| SCHEMBL9714554 | 0.78 | HPGD (0.89) | HPGDSMN1; SMN2POLBABCB1CYP3A4 | |
| SCHEMBL8773650 | 0.78 | HPGD (0.89) | HPGDSMN1; SMN2POLBABCB1CYP3A4 | |
| SCHEMBL9825414 | 0.77 | CYP2C9 (0.48) | HPGDCYP3A4 | |
| SCHEMBL9496095 | 0.77 | MEN1 (0.51) | HPGDCYP3A4 | |
| SCHEMBL9825688 | 0.76 | POLB (0.53) | HDAC1HDAC6HDAC3HDAC7HDAC8 | |
| SCHEMBL9876990 | 0.76 | POLB (0.53) | HDAC1HDAC6HDAC3HDAC7HDAC8 | |
| SCHEMBL9426049 | 0.75 | HTT (0.50) | SMN1; SMN2HDAC1HDAC6CYP3A4 | |
| SCHEMBL13678990 | 0.74 | EPHX2 (0.45) | HPGDSMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0236618-A2 | Insecticidal N'-substituted-N,N'-diacylhydrazines | ROHM AND HAAS COMPANY (US) | 1987-09-16 | — | — | EP | disclosed |