Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.48 |
| ▸ | GRN | P28799 | 1/20 | 0.47 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | S1PR3 | Q99500 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9825414 | 0.95 | CYP2C9 (0.48) | MEN1KMT2ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL8177791 | 0.84 | POLB (0.56) | KMT2ACYP2C9LMNACYP3A4 | |
| SCHEMBL9241810 | 0.78 | POLB (0.71) | MEN1KMT2ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9825031 | 0.78 | KMT2A (0.42) | MEN1KMT2ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL10718347 | 0.78 | CYP3A4 (0.43) | KMT2ACYP2C9LMNACYP3A4 | |
| SCHEMBL10721764 | 0.77 | HPGD (0.55) | HPGDCYP3A4 | |
| SCHEMBL9342048 | 0.73 | CYP3A4 (0.74) | MEN1KMT2ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL10957796 | 0.73 | MLYCD (0.51) | MEN1KMT2ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9825688 | 0.72 | POLB (0.53) | KMT2ACYP2C9LMNACYP3A4 | |
| SCHEMBL9876990 | 0.72 | POLB (0.53) | KMT2ACYP2C9LMNACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5237099-A | Insecticidal substituted and unsubstituted benzoic acid 1-alkyl, 2-alkyl and 2-cycloalkylhydrazides | AMERICAN CYANAMID COMPANY (US) | 1993-08-17 | — | — | US | disclosed |
| US-4814349-A | Insecticidal substituted and unsubstituted benzoic acid 1-alkyl, 2 alkyl and 2-cycloalkylhydrazides | AMERICAN CYANAMID COMPANY (US) | 1989-03-21 | — | — | US | disclosed |
| EP-0228564-A2 | Novel insecticidal diacylhydrazine compounds | AMERICAN CYANAMID COMPANY (US) | 1987-07-15 | — | — | EP | disclosed |