Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | PDE4A | P27815 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16005657 | 0.93 | NPSR1 (0.44) | LMNASMN1; SMN2MAPTPDE4ACYP1A2 | |
| SCHEMBL16005728 | 0.83 | SMN1; SMN2 (0.39) | LMNASMN1; SMN2MAPTPDE4AALDH1A1 | |
| SCHEMBL10726504 | 0.82 | LMNA (0.52) | LMNASMN1; SMN2MAPTPDE4ACYP1A2 | |
| SCHEMBL10721484 | 0.82 | NPSR1 (0.58) | LMNASMN1; SMN2MAPTPDE4ACYP1A2 | |
| SCHEMBL10619199 | 0.80 | SMN1; SMN2 (0.74) | LMNASMN1; SMN2MAPTPDE4ACYP1A2 | |
| SCHEMBL16005423 | 0.78 | MEN1 (0.39) | SMN1; SMN2MAPTPDE4ACYP1A2KMT2A | |
| SCHEMBL10721766 | 0.74 | LMNA (0.48) | LMNASMN1; SMN2MAPTPDE4ACYP1A2 | |
| SCHEMBL16005592 | 0.71 | NPSR1 (0.43) | LMNASMN1; SMN2MAPTPDE4ACYP1A2 | |
| SCHEMBL14438979 | 0.70 | PDE4A (0.78) | LMNASMN1; SMN2MAPTPDE4ACYP1A2 | |
| SCHEMBL19687642 | 0.70 | LMNA (0.68) | LMNASMN1; SMN2MAPTPDE4ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0240854-A1 | Bis-tert-butylamino-substituted 1,3,5-triazine derivatives, process for their preparation, medicaments containing these compounds, and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-10-14 | — | — | EP | disclosed |