Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.47 |
| ▸ | GAA | P10253 | 9/20 | 0.47 |
| ▸ | MAPT | P10636 | 9/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.47 |
| ▸ | RAD52 | P43351 | 3/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10721399 | 0.86 | KDM4E (0.43) | LMNASMN1; SMN2KMT2AKDM4EGAA | |
| SCHEMBL10722121 | 0.85 | KMT2A (0.47) | LMNASMN1; SMN2KMT2ARAB9AKDM4E | |
| SCHEMBL10721458 | 0.83 | LMNA (0.47) | LMNASMN1; SMN2KMT2ARAB9AKDM4E | |
| SCHEMBL10721522 | 0.82 | LMNA (0.49) | LMNASMN1; SMN2KMT2ARAB9AKDM4E | |
| SCHEMBL10725132 | 0.82 | LMNA (0.52) | LMNASMN1; SMN2KMT2ARAB9AKDM4E | |
| SCHEMBL10724754 | 0.81 | LMNA (0.56) | LMNASMN1; SMN2KMT2ARAB9AKDM4E | |
| SCHEMBL10722302 | 0.79 | MAPT (0.39) | LMNASMN1; SMN2KDM4EMAPTALDH1A1 | |
| SCHEMBL10725769 | 0.79 | KMT2A (0.57) | LMNASMN1; SMN2KMT2ARAB9AKDM4E | |
| SCHEMBL10725982 | 0.76 | LMNA (0.51) | LMNASMN1; SMN2KMT2ARAB9AKDM4E | |
| SCHEMBL10721505 | 0.76 | LMNA (0.51) | LMNASMN1; SMN2KMT2ARAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4649149-A | ANTHELMINTICS | CIBA-GEIGY CORPORATION (US) | 1987-03-10 | — | — | US | disclosed |
| US-4511567-A | ANTHELMINTICS | CIBA-GEIGY CORPORATION (US) | 1985-04-16 | — | — | US | disclosed |
| EP-0041046-A1 | Benzazol derivatives, processes for their preparation, their pharmaceutical composition and their application | CIBA-GEIGY AG (CH) | 1981-12-02 | — | — | EP | disclosed |