Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3938764 | 0.81 | SMN1; SMN2 (0.53) | MAPTCYP2C19ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL29015042 | 0.81 | MAPT (0.53) | MAPTCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL31455595 | 0.80 | CYP4F2 (0.52) | MAPTCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL8115498 | 0.80 | TSHR (0.55) | MAPTCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL8114167 | 0.80 | CYP4F2 (0.52) | MAPTCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL397968 | 0.79 | CYP4F2 (0.51) | MAPTCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL132039 | 0.79 | CA2 (0.64) | MEN1KMT2ATSHRCA2 | |
| SCHEMBL28448724 | 0.77 | CA2 (0.53) | MAPTCYP1A2CYP3A4CYP2D6CYP2C9 | |
| Lithium Ion SCHEMBL28897638 | 0.77 | CA2 (0.53) | MAPTCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL29427226 | 0.77 | CYP4F2 (0.63) | CYP1A2CYP2C9CYP2C19ALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4673686-A | CNS MODIFIERS, ANTI-APOMORPHINE ANTIENETIC ACITIVTY/ | SOCIETE D'ETUDES SCIENTIFIQUES ET INDUSTRIELLE DE L'ILE DE FRANCE (FR) | 1987-06-16 | — | — | US | disclosed |